Academic Organization


http://www.dent.niigata-u.ac.jp/prosth2/profile-e.html




- Basic Research in Dental Implant
- Clinical Research in Dental Implant
- Clinical Research in Metal Allergy
- Effect of Existing Bone Quality on Bone Metabolism
- Bone Augmentation Using Regulation of Cell Differentiation
- Stress Analysis Using 3D Finite Element Model
- Stem Cells in Periodontal Ligament.
- Phenotype Induction in Bone Biology
- Education in Prosthdontics
- Biological Features of Periodontal Ligament




Katsumi UOSHIMAProfessorsecond department of prosthetic dentistry, faculty of dentistry
Masaru KAKUAssociate Professorsecond department of prosthetic dentistry, faculty of dentistry
Yosuke AKIBALecturersecond department of prosthetic dentistry, faculty of dentistry
Maiko KAWASAKIAssistant Professorsecond department of prosthetic dentistry, faculty of dentistry
Nami AKIBAAssistant Professorsecond department of prosthetic dentistry, faculty of dentistry
Masako NAGASAWAAssistant Professorsecond department of prosthetic dentistry, faculty of dentistry
Juan Marcelo Rosales ROCABADOAssistant Professorsecond department of prosthetic dentistry, faculty of dentistry
Yujin AOYAGIAssistant Professorsecond department of prosthetic dentistry, faculty of dentistry
Sakiko KAKUResidentsecond department of prosthetic dentistry, faculty of dentistry
Ryouhei TAKANOPart-time Lecturersecond department of prosthetic dentistry, faculty of dentistry
Megumi KITAMIPostdoctoral Fellowsecond department of prosthetic dentistry, faculty of dentistry
Idrees Nasri HAIDARIANGraduate Studentsecond department of prosthetic dentistry, faculty of dentistry
Takako IDAGraduate Studentsecond department of prosthetic dentistry, faculty of dentistry
Kaori EGUCHIGraduate Studentsecond department of prosthetic dentistry, faculty of dentistry
Kazutaka MIZUSHIMAInternsecond department of prosthetic dentistry, faculty of dentistry





Kaku M and Uoshima K / Implant System Selection and Treatment Planning. / World Congress for Oral Implantology / WCOI Year Book 2009 (CD version) / 1st ed. / WCOI / - / 2009 / 57 / 63 /



Kaku M, Rocabado JMR, Kitami M, Ida T, Uoshima K: Royal jelly affects collagen crosslinking in bone of ovariectomized rats. / Royal jelly affects collagen crosslinking in bone of ovariectomized rats / J Functional Foods / 7 / 398 / 406 / 2014 / Online Journal

Rocabado JMR, Kaku M, Kitami M, Akiba Y, Katsumi Uoshima / Osteoblastic Differentiation and Mineralization Ability of periosteum-Derived Cells Compared With Bone Marrow and Calvaria-Derived Cells / J Oral Maxillofac Surg / 72 / 694.e-1 / 694.e-9 / 2014 / Online Journal

Angelova Volponi A, Kawasaki M, Sharpe PT / Adult Human Gingival Epithelial Cells as a Source for Whole-tooth Bioengineering / J Dent Res / 92 / 329 / 334 / 2013 / Online Journal

Khonsari RH, Ohazama A, Raouf R, Kawasaki M, Kawasaki K, Porntaveetus T, Ghafoor S, Hammond P, Suttie M, Odri GA, Sandford RN, Wood JN, Sharpe PT / Multiple postnatal craniofacial anomalies are characterized by conditional loss of polycystic kidney disease 2 (Pkd2) / Hum Mol Genet / 22 / 1873 / 1885 / 2013 / Online Journal

Otsuka-Tanaka Y, Oommen S, Kawasaki M, Kawasaki K, Imam N, Jalani-Ghazani F, Hindges R, Sharpe PT, Ohazama A / Oral lining mucosa development depends on mesenchymal microRNAs / J Dent Res / 92(3) / 229 / 234 / 2013 / Online Journal

Khonsari RH, Seppala M, Pradel A, Dutel H, Clément G, Lebedev O, Ghafoor S, Rothova M, Tucker A, Maisey JG, Fan CM, Kawasaki M, Ohazama A, Tafforeau P, Franco B, Helms J, Haycraft CJ, David A, Janvier P, Cobourne MT, Sharpe PT / The buccohypophyseal canal is an ancestral vertebrate trait maintained by modulation in sonic hedgehog signaling / BMC Biol / 11(1) / 11 / 27 / 2013 / Online Journal

Oommen S, Francois M, Kawasaki M, Murrell M, Kawasaki K, Porntaveetus T, Ghafoor S, Young NJ, Okamatsu Y, McGrath J, Koopman P, Sharpe PT, Ohazama A / Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function. / PLoS One / 7(9) / e43857 / e43857 / 2012 / Online Journal

Oommen S, Otsuka-Tanaka Y, Imam N, Kawasaki M, Kawasaki K, Jalani-Ghazani F, Anderegg A, Awatramani R, Hindges R, Sharpe PT, Ohazama A / Distinct roles of microRNAs in epithelium and mesenchyme during tooth development / Dev Dyn / 241(9) / 1465 / 1472 / 2012 / Online Journal

Kaku M, Komatsu Y, Mochida Y, Yamauchi M, Mishina Y, Ko CC / Identification and characterization of neural crest-derived cells in adult periodontal ligament of mice / Arch Oral Bio / 57(12) / 1668 / 1675 / 2012 / Online Journal

Blackburn J, Ohazama A, Kawasaki K, Otsuka-Tanaka Y, Liu B, Honda K, Rountree RB, Hu Y, Kawasaki M, Birchmeier W, Schmidt-Ullrich R, Kinoshita A, Schutte BC, Hammond NL, Dixon MJ, Sharpe PT / The role of Irf6 in tooth epithelial invagination / Developmental Biology / 365 / 61 / 70 / 2012 / Online Journal

Arasawa M, Oda Y, Kobayashi T, Uoshima K, Nishiyama H, Hoshina H, Saito C / Evaluation of bone volume changes after sinus floor augmentation with autogenous bone grafts. / Int J Oral Maxillofac Surg / 41(7) / 853 / 857 / 2012 / Online Journal

Kawasaki M, Nomura S, Okada N, Nomura A, Uoshima K / Evaluation of newly developed devices for denture placement and removal in the dependent elderly / Gerodontology / 29 / e703 / e709 / 2011 / Online Journal

Nagasawa M, Takano R, Maeda T, Uoshima K / Observation of the Bone Surrounding Overloaded Implant in a Novel Rat Model / Int J Oral Maxillofac Implants / 28(1) / 109 / 116 / 2011 / Online Journal

Mochida Y, Kaku M, Yoshida K, Katafuchi M, Atsawasuwan P, Yamauchi M. / Podocan-like protein: a novel small leucine-rich repeat matrix protein in bone / Biochem Biophys Res Commun. / 410(2) / 333 / 338 / 2011 / Online Journal

Boushell LW, Kaku M, Mochida Y, Yamauchi M / Distribution and relative activity of matrix metalloproteinase-2 in human coronal dentin / Int J Oral Sci. / 3(4) / 192 / 199 / 2011 / Online Journal

Kawasaki K, Porntaveetus T, Oommen S, Ghafoor S, Kawasaki M, Otsuka-Tanaka Y, Blackburn J, Kessler JA, Sharpe PT, Ohazama A / Bmp signaling in filiform tongue papillae development / Archives of oral biology / 57(6) / 805 / 813 / 2011 / Online Journal

Akiba Y, Tomizuka K, Kaku M, Kawasaki M, Nagasawa M, Takano R, Uoshima K / Analysis of patients visiting Niigata Medical and Dental Hospital with chief complaints of dental metal allergy and/or dental focal infection in the previous 8 years. / The Indonesian Journal of Dental Research / 1(2) / 109 / 115 / 2011 / Online Journal

Takano R, Stegaroiu R, Nagasawa M, Uoshima K / Towards the establishment of a 3-D finite element model to investigate stress distribution around an implant under excessive load in a rat model: optimal implant location and dimensions / Revista Romana de Stomatologie (Ro J Stomatol) / 57(1) / 62 / 66 / 2010 / Online Journal

Cave JW, Akiba Y, Banerjee K, Bhosle S, Berlin R, Baker H. / Differential regulation of dopaminergic gene expression by er81. / J Neurosci / 30(13) / 4717 / 4724 / 2010 / Online Journal

Akiba Y, Cave JW, Akiba N, Langley B, Ratan RR, Baker H. / Histone deacetylase inhibitors de-repress tyrosine hydroxylase expression in the olfactory bulb and rostral migratory stream. / Biochem Biophys Res Commun. / 393(4) / 673 / 677 / 2010 / Online Journal

K. Yoshida, K. Uoshima, K. Oda, T. Maeda / Influence of heat stress to matrix on bone formation / Clin Oral Implants Res / 20(8) / 782 / 790 / 2009 / Online Journal

Nozaki K, Kaku M, Yamashita Y, Yamauchi M, Miura H / Effect of Cyclic Mechanical Loading on Osteoclast Recruitment in Periodontal Tissue / J Periodontal Res / 45(1) / 8 / 15 / 2009 / Online Journal

Akiba, N., Akiba, Y., Jo, S., Baker, H., Cave, JW. J. / Expression of EGR-1 in a subset of olfactory bulb dopaminergic cells / J. Mol. Histology / 40(2) / 151 / 155 / 2009 / Online Journal

Akiba Y, Sasaki H, Huerta PT, Estevez AG, Baker H, Cave JW / gamma-Aminobutyric acid-mediated regulation of the activity-dependent olfactory bulb dopaminergic phenotype / J Neurosci Res / 87(10) / 2211 / 2221 / 2009 / Online Journal

Nakadate M, Amizuka N, Oda K, Nomura S, Uoshima K, Maeda T / Histological Evaluation on Bone Regeneration with Self-Setting Alpha-TCP Cement at Dental Implant Placement Sites / Microscopy Research and Technique / 71 / 93 / 104 / 2008 / Online Journal

Haga M,Fujii N,Nozawa-Inoue K,Nomura S,Oda K,Uoshima K,Maeda T / Detailed Process of Bone Remodeling after Achievement of Osseointegration in the Rat Implantation Model. / Anat.Rec / 292 / 38 / 47 / 2008 / Online Journal

E. Corbet, J. Akinwade, R. Duggal, G. Gebreegziabher, H. Hirvikangas, D. Hysi, L. Katrova, T. Karaharju-Suvanto, C. McGrath, K. Ono, M. Radnai, E. Schwarz, J. Scott, J.-L. Sixou, U. Soboleva, K. Uoshima, K. Yaneva-Ribagina and C. Fox / Staff recruitment, development and global mobility / Eur J Dent Educ / 12 (suppl 1) / 149 / 160 / 2008 / Online Journal

Sakai Y, Sugita K, Kawasaki M, Nomura S, Igarashi A / Effects of Hardness, Taste and Amount of Low-Gel-Strength Ager on Swallowing in Young and Elderly Subjects. / J. Home Econ Jpn / 60 (2) / 133 / 138 / 2008 / Online Journal

Tsuchiya M, Akiba Y, Takahashi I, Sasano Y, Kashiwazaki J, Tsuchiya S, Watanabe M / Comparison of expression patterns of cathepsin K and MMP-9 in odontoclasts and osteoclasts in physiological root resorption in the rat molar. / Arch Histol Cytol. / 71 (2) / 89 / 100 / 2008 / Online Journal

Nagaoka H, Mochida Y, Atsawasuwan P, Kaku M, Kondoh T, Yamauchi M. / 1,25(OH)(2)D(3) regulates collagen quality in an osteoblastic cell culture system. / Biochem Biophys Res Commun. / 377 (2) / 674 / 678 / 2008 / Online Journal

Atsawasuwan P, Mochida Y, Katafuchi M, Kaku M, Fong S K K, Csiszar K., and Yamauchi M, / Lysyl oxidase binds transforming growth factor-beta and regulates its signaling via amine oxidase activity / J. Biol. Chem / 283 (49) / 34229 / 34240 / 2008 / Online Journal

Boushell LW, Kaku M, Mochida Y., Bagnell R, Yamauchi M., / Immunohistochemical Localization of Matrixmetalloproteinase-2 in Human Coronal Dentin / Arch Oral Biol / 53 (2) / 109 / 116 / 2008 / Online Journal

T. Maeda, K. Ono, A. Ohuchi, T. Hayashi, I. Saito, T. Okiji and K. Uoshima / Evaluation of Problem-based Learning Course at the Niigata University Faculty of Dentistry / Dentistry in Japan / 43 / 166 / 171 / 2007 / Online Journal

Saino-Saito S, Cave JW, Akiba Y, Sasaki H, Goto K, Kobayashi K, Berlin R, Baker H / ER81 and CaMKIV identify anatomically and phenotypically defined subsets of mouse olfactory bulb interneurons / J Comp Neurol / 502 (4) / 485 / 496 / 2007 / Online Journal

Fishbein K.W., Gluzband Y.A., Kaku M., Ambia-Sobhan H., Shapses S.A., Yamauchi M., and Spencer R.G. / The Effects of Formalin Fixation and Collagen Crosslinking on T2 and Magnetization Transfer in Bovine Nasal Cartilage / Magn Reson Med / 57 (6) / 1000 / 1011 / 2007 / Online Journal

Kaku M., Mochida Y., Atsawasuwan P., Parisuthiman D. Yamauchi M. / Post-translational modifications of collagen upon BMP induced osteoblast differentiation / Biochem Biophys Res Commun / 359 (3) / 463 / 468 / 2007 / Online Journal

Akiba Y, Sasaki H, Saino-Saito S, Baker H / Temporal and spatial disparity in cFOS expression and dopamine phenotypic differentiation in the neonatal mouse olfactory bulb / Neurochem Res / 32 (4-5) / 625 / 635 / 2006 / Online Journal

Mochida Y, Parisuthiman D, Kaku M, Hanai JI, Sukhatme VP, Yamauchi M. / Nephrocan, a novel member of the small leucine-rich repeat protein family, is an inhibitor of transforming growth factor-beta signaling / J. Biol. Chem / 281 (47) / 36044 / 36051 / 2006 / Online Journal

N. Fujii, K. Uoshima, T. Maeada / Regeneration of Epithelium and Nerve Fibers Incident to Implantation - Neuronal Similarity between Peri-Implant and Junctional Epithelium - / J. Oral Tissue Engineering / 2 (2) / 51 / 59 / 2005 / Online Journal

M. Kaku, K. Uoshima, Y. Yamashita, H. Miura / Investigation of Periodontal Ligament Reaction upon Excessive Occlusal Load― Osteopontin Induction among Periodontal Ligament Cells ― / J. Periodont. Res / 40 / 59 / 66 / 2005 / Online Journal

S. Arwatchanakan, K. Uoshima, H. Takahashi and H. Miura / The effect of electrical potential on the penetration of metal ions through radicular dentin. / Journal of Medical and Dental Sciences / 51 (1) / 53 / 58 / 2005 / Online Journal

Tapety F.I., Amizuka N., Uoshima K., Nomura S., and T. Maeda / A Histological Evaluation on the Involvement of Bio-Oss® in Osteoblastic Differentiation and Matrix Synthesis / Clinical Oral Implants Research / 15(3) / 315 / 324 / 2004 / Online Journal

Akiba Y, Suzuki R, Saito-Saino S, Owada Y, Sakagami H, Watanabe M, Kondo H. / Localization of mRNAs for phosphatidylinositol phosphate kinases in the mouse brain during development / Brain Res Gene Expr Patterns / 1 (2) / 123 / 133 / 2002 / Online Journal

B. J. Baum, J. Scott, M. Bickel, G. Gombos, J. S. Greenspan, W. Guo, N.-H. Park, D. Purdell-Lewis, R. Ranney, E. Schwarz, G. Seymour and K. Uoshima / Global challenges in research and strategic planning / European Journal of Dental Education / 6 (s3) / 179 / 184 / 2002 / Online Journal

L. F. Cooper, K. Uoshima and Z. Guo / Transcriptional regulation involving the intronic heat shock element of the rat hsp27 gene / Biochimica et Biophysica Acta / 1490 / 348 / 354 / 2000 / Online Journal

Takato,T., Yonehara,Y., Susami,T. and Uoshima,K. / Modification of the Abbe flap for reconstruction of the vermilion tubercle and Cupid's bow in cleft lip patients / J.Oral and Maxillofac. Surg., / 54 (3) / 256 / 262 / 1996 / Online Journal

Uoshima,K., Cooper,L.F. / Rat hsp27 expression pattern indicates the complex regulation of hsp27 gene expression / Jpn.J.Oral Biol / 38 (1) / 145 / 148 / 1996 / Online Journal

Yliheikkila,P.K., Felton,D.A., Whitson,S.W., Ambrose,W.W., Uoshima,K., Cooper,L.F. / Correlative Microscopic Investigation of the Interface Between Titanium Alloy and the Osteoblast-Osteoblast Matrix Using Mineralizing Cultures of Primary Fetal Bovine Mandibular Osteoblasts. / Int.J.Oral.Maxillofac.Implants / 10 / 655 / 665 / 1995 / Online Journal

Cooper,L.F., Uoshima,K. / Differential Estrogenic Regulation of Small Mr Heat Shock Protein Expression in Osteoblasts / J.Biol.Chem / 269 (11) / 7869 / 7873 / 1994 / Online Journal

Takato,T., Harii,K., Yonehara,Y., Komuro,Y., Susami,T., Uoshima,K. / Correction of the Cleft Nasal Deformity with an L-shaped Iliac Bone Graft / Annals. of Plastic Surgery / 33 (5) / 486 / 493 / 1994 / Online Journal

Uoshima,K., Handelman,B., Cooper,L.F. / Isolation and characterization of a rat HSP 27 gene. / Biochem. Biophys. Res. Comm / 197 (3) / 1388 / 1395 / 1993 / Online Journal

Komori,T., Uoshima,K., et al / Multiple primary Carcinoma of the Palate, Report of a Case. / Asian J. Oral Maxillofac. Surg / 5 / 37 / 40 / 1993 / Online Journal






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