Academic Organization

Pediatric Dentistry






- The efficient generation of iPS cells derived from the oral tissue

We perform a trial to apply the primarily cultured cells from the oral tissue of children to regenerative medicine. For example, primary teeth were disposed by replacement of teeth. But the primary cultured cells from primary teeth in children are useful for the research of stem cells. However it is necessary to solve some big problems. Above all, there are not enough to use cells provided from deciduous tooth and other tissue for regenerative medicine. Therefore we develop the technique to generate iPS cells derived from the oral tissue of children effectively.

- Development of food intake and masticatory function in children

Food intake behavior is one of the most important functions of the mandible. Therefore, the knowledge concerning on the changes during growth of this function is essential knowledge for the dental professionals. However, details on this function have not been elucidated even in the adult. Accordingly, one of research interests of our department is to elucidate 1) weaning period, 2) process of establishing food intake function during growth, and also 3) coordinated motion among the mandible, head, arm and body during this behavior at each different stages. High resolution three-dimensional motion capture system is used to analyze these phenomena.

- Physiological mechanism of tooth brushing

Tooth brushing is most generally used method of oral hygiene. However, its detailed motion has not been clarified. This research aims to elucidate the physiological mechanism of tooth brushing by analyzing the 3-dimensional motion, tooth brushing force, plaque removal efficacy and so on.

- Clinical research on maxillofacial morphology and lip function in children
- Three-dimentional analysis of face development
- Clinical and basic research on mouth breathing in children
- Behavior Management by Using Nitrous Oxide Inhalation and Lidocaine with Dexmedetomidine
- Behavior control and systemic management during dental treatment in children and people with special needs
- The study of the oral health condition of abused children
- Kinematic and neurophysiological study of feeding behavior
- Development of efficient isolation method of tissue specific stem cells by genetic engineering procedure
- Research on the dynamics of dental pulp stem cells during pulpal healing after tooth injuries
- Research on the toxins secreted by Group A Streptococcus (bactria which causes pharyngitis of children)
- The detection of the novel reagents for controlling biofilm produced by Streptococcus mutans (bacteria which causes caries)




Haruaki HAYASAKIChair & ProfessorPediatric dentistry, faculty of dentistry
Issei SaitohAssociate ProfessorPediatric dentistry, faculty of dentistry
Kuniko OHSHIMALecturerPediatric dentistry, faculty of dentistry
Yoko IWASEAssistant ProfessorPediatric dentistry, faculty of dentistry
Yuki NAKAMUAAssistant ProfessorPediatric dentistry, faculty of dentistry
Tomoya MURAKAMIAssistant ProfessorPediatric dentistry, faculty of dentistry
Mie KUROSAWAAssistant ProfessorPediatric dentistry, faculty of dentistry
Nozomi MURAKAMISpecially Appointed Assistant ProfessorPediatric dentistry, faculty of dentistry
Tadashi SAWAMIClinical ResidentPediatric dentistry, faculty of dentistry
Tsutomu NAKAJIMAClinical ResidentPediatric dentistry, faculty of dentistry
Miki SodaGraduate StudentPediatric dentistry, faculty of dentistry
Ayako SUZUKIGraduate StudentPediatric dentistry, faculty of dentistry
Kazunari MATSUEDAGraduate StudentPediatric dentistry, faculty of dentistry
Yuki SASAKAWAGraduate StudentPediatric dentistry, faculty of dentistry
Yukiko NOGAMIGraduate StudentPediatric dentistry, faculty of dentistry
Naomi MARUYAMAGraduate StudentPediatric dentistry, faculty of dentistry
Tomoyo MURAIGraduate StudentPediatric dentistry, faculty of dentistry
Saki ONODERAResidentPediatric dentistry, faculty of dentistry
Masami KIMIResearch WorkerPediatric dentistry, faculty of dentistry
Mikiko HIRAHARAResearch WorkerPediatric dentistry, faculty of dentistry
Katsuya OGATAAdjunct InstructorPediatric dentistry, faculty of dentistry
Yasutaka YAWAKAAdjunct InstructorPediatric dentistry, faculty of dentistry
Takeshi OKUAdjunct InstructorPediatric dentistry, faculty of dentistry
Ryuzo KANOMIAdjunct InstructorPediatric dentistry, faculty of dentistry
Hiroshi YAMAZAKIAdjunct InstructorPediatric dentistry, faculty of dentistry
Hidehiro UMETSUAdjunct InstructorPediatric dentistry, faculty of dentistry
Seiji KOSUGIAdjunct InstructorPediatric dentistry, faculty of dentistry
Yuuka ISHIKURAAdjunct InstructorPediatric dentistry, faculty of dentistry
Tokuhito ISHITANIAdjunct InstructorPediatric dentistry, faculty of dentistry
Junko MATSUYAMAAdjunct InstructorPediatric dentistry, faculty of dentistry







Saitoh, I., Sato, M., Soda, M., Inada, E., Iwase, Y., Murakami, T., Ohshima, H., Hayasaki, H., Noguchi, H. / Tissue-specific stem cells obtained by reprogramming of non-obese diabetic (NOD) mouse-derived pancreatic cells confer insulin production in response to glucose. / PLoS One / Article ID: e0163580 / / / 2016 / Online Journal

Morizono, K., Takemoto, Y., Inada, E., Murakami, D., Saitoh, I., Sato, H., Iwasaki, T., Yamasaki, Y. / Simultaneous evaluation of three-dimensional lip kinetics and tongue pressure during swallowing. / Int. J. Dent. Oral Health / / / / 2016 / Online Journal

Inada, E., Saitoh, I., Kubota, N., Murakami, T., Soda, M., Sawami, T., Yamasaki, Y., Sato, M. / Alkaline phosphatase and OCT-3/4 as useful markers for predicting susceptibility of human deciduous teeth-derived dental pulp cells to reprogramming factor-induced iPS cells. / J. Investig. Clin. Dent. / / / / 2016 / Online Journal

Sato, M., Maeda, K., Koriyama, M., Inada, E., Saitoh, I., Ohtsuka, M., Nakamura, S., Sakurai, T., Watanabe, S., Miyoshi, K. / The piggyBac-based gene delivery system can confer successful production of cloned porcine blastocysts with multigene constructs. / Int. J. Mol. Sci. / / / / 2016 / Online Journal

Sato, M., Saitoh, I., Inada, E. / Efficient CRISPR/Cas9-based gene correction in induced pluripotent stem cells established from fibroblasts of patients with sickle cell disease. / Stem. Cell. Investigation / / / / 2016 / Online Journal

Miyagi-Shiohira, C., Kobayashi, N., Saitoh, I., Watanabe, M., Noguchi, Y., Matsushita, M., Noguchi, H. / Comparison of purification solutions with different osmolality for porcine islet purification. / Cell. Med. / 9 / 53 / 59 / 2016 / Online Journal

Miyagi-Shiohira, C., Kobayashi, N., Saitoh, I., Watanabe, M., Noguchi, Y., Matsushita, M., Noguchi, H. / Evaluation of islet purification methods using large bottles to make continuous density gradient. / Cell. Med. / 9 / 45 / 51 / 2016 / Online Journal

Miyagi-Shiohira, C., Kobayashi, N., Saitoh, I., Watanabe, M., Noguchi, Y., Matsushita, M., Noguchi, H. / Evaluation of serum-free, xeno-free cryopreservation solutions for human adipose-derived mesenchymal stem cells. / Cell. Med. / 9 / 15 / 20 / 2016 / Online Journal

Kurosawa, M., Oda, M., Domon, H., Saitoh, I., Hayasaki, H., Terao, Y. / Streptococcus pyogenes CAMP factor attenuates phagocytic activity of RAW 264.7 cells. / Microbes. Infect. / 18 / 118 / 127 / 2016 / Online Journal

Nakamura, Y., Masuda, K., Yamaza, H., Nonaka, K. / Central odontogenic fibroma associated with eruption disturbance of a permanent incisor in a six-year-old girl. / Int. J. Dentistry Oral Sci. / 3 / 205 / 208 / 2016 / Online Journal

Tsujimura, T., Tsuji, K., Magara, J., Sakai, S., Suzuki, T., Nakamura, Y., Nozawa-Inoue, K., Inoue, M. / Differential response properties of peripherally and cortically evoked swallows by electrical stimulation in anesthetized rats. / Brain Res. Bull. / 122 / 12 / 18 / 2016 / Online Journal

Hayashi-Sakai, S., Numa-Kinjoh, N., Sakamoto, M., Sakai, J., Matsuyama, J., Mitomi, M., Sano-Asahito, T., Kinoshita-Kawano, S. / Non-destructive evaluation of size and mineral density in exfoliated teeth with hypophosphatasia: a case report. / J. Clin. Pediatr. Dent. / Article ID 4898456 / / / 2016 / Online Journal

Iwasaki, T., Sato, H., Suga, H., Takemoto, Y., Inada, E., Saitoh, I., Kakuno, E., Kanomi, R., Yamasaki, Y. / Relationships between nasal resistance, adenoids, tonsils, and tongue posture and maxillofacial form in Class II and Class III children. / American Journal of Orthodontics and Dentofacial Orthopedics / / in press / / 2016 /

Miyagi-Shiohira, C., Kurima, K., Kobayashi, N., Saitoh, I., Watanabe, M., Noguchi, Y., Matsushita, M., Noguchi, H. / Cryopreservation of adipose-derived mesenchymal stem cells (Review). / Cell. Med. / / in press / / 2016 /

Saitoh, I., Fukumoto, S., Iwase, Y., Hayasaki, H., Youichi, Y / Unilateral open-bite caused by impacted tooth of deciduous molar with the ankylosis: A Case Report. / Pediatric Dental Journal / / in press / / 2016 /

Tsugata, T., Nikoh, N., Tatsuya, Kin., Saitoh, I., Noguchi, Y., Ueki, H., Watanabe, M., James, Shapiro A., Noguchi, N. / Potential factors for the differentiation of ES/iPS cells into insulin-producing cells. / Cell Med. / 7 / 83 / 93 / 2015 / Online Journal

Inada, E., Saitoh, I., Yong, Y., Tomiyama, D., Murakami, D., Takemoto, Y., Morizono, K., Iwasaki, T., Yamasaki, Y. / Quantitative evaluation of toothbrush and arm-joint motion during tooth brushing. / Clin. Oral Investig. / 19 / 1451 / 1462 / 2015 / Online Journal

Sato, M., Inada, E., Saitoh, I., Matsumoto, Y., Ohtsuka, M., Miura, H., Nakamura, S., Sakurai, T., Watanabe, S. / A combination of targeted toxin technology and the piggyBac-mediated gene transfer system enables efficient isolation of stable transfectants in nonhuman mammalian cells. / Biotechnol. J. / 10 / 143 / 153 / 2015 / Online Journal

Saitoh, I., Inada, E., Iwase, Y., Noguchi, H., Murakami, T., Soda, M., Kubota, N., Hasegawa, H., Akasaka, E., Matsumoto, Y., Oka, K., Yamasaki, Y., Hayasaki, H., Sato, M. / Choice of feeders is important for the preparation of iPS cells from primarily cultured human deciduous tooth dental pulp cells. / Cell Med. / 8 / 9 / 23 / 2015 / Online Journal

Inada, E., Saitoh, I., Miura, H., Ohtsuka, M., Murakami, T., Sawami, T., Yamasaki, Y., Watanabe, S., Aoki, R., Sato, M. / PiggyBac transposon-mediated gene delivery efficiently generates stable transfectants derived from cultured primary human deciduous tooth dental pulp cells (HDDPCs) and HDDPC-derived iPS cells. / Int. J. Oral Sci. / 7 / 144 / 154 / 2015 / Online Journal

Sato, M., Koriyama, M., Watanabe, S., Ohtsuka, M., Sakurai, T., Inada, E., Saitoh, I., Nakamura, S., Miyoshi, K. / Direct injection of CRISPR/Cas9-related mRNA into cytoplasm of parthenogenetically activated porcine oocytes causes frequent mosaicism for indel mutations. / Int. J. Mol. Sci. / 16 / 17838 / 17856 / 2015 / Online Journal

Miyagi-Shiohira, C., Kurima, K., Kobayashi, N., Saitoh, I., Watanabe, M., Noguchi, Y., Matsushita, M., Noguchi, H. / Cryopreservation of adipose-derived mesenchymal stem cells. / Cell Med. / 8 / 3 / 7 / 2015 / Online Journal

Noguchi, H., Miyagi-Shiohira, C., Kurima, K., Kobayashi, N., Saitoh, I., Watanabe, M., Noguchi, Y., Matsushita, M. / Islet culture/preservation before islet transplantation (Review). / Cell Med. / 8 / 25 / 29 / 2015 / Online Journal

Sato, M., Kagoshima, A., Saitoh, I., Inada, E., Miyoshi, K., Ohtsuka, M., Nakamura, S., Sakurai, T., Watanabe, S. / Generation of α-1,3-galactosyltransferase-deficient porcine embryonic fibroblasts by CRISPR/Cas9-mediated knock-in of a small mutated sequence and a targeted toxin-absed selection system. / Reprod. Domest. Anim. / 50 / 872 / 880 / 2015 / Online Journal

Sano-Asahito, T., Suzuki, A., Matsuyama, J., Mitomi, T., Kinoshita-Kawano, S., Hayashi-Sakai, S., Asahito, T. / Self-esteem and oral condition of institutionalized abused children in Japan. / J. Clin. Pediatr. Dent. / 39 / 322 / 325 / 2015 / Online Journal

Noguchi, H., Saitoh, I., Tsugata, T., Kataoka, H., Watanabe, M., Noguchi, Y. / Induction of tissue-specific stem cells by reprogramming factors, and tissue-specific selection. / Cell Death Differ. / 22 / 145 / 155 / 2015 / Online Journal

Sato, M., Inada, E., Saitoh, I., Matsumoto, Y., Ohtsuka, M., Miura, H., Nakamura, S., Sakurai, T., Watanabe, S. / A combination of targeted toxin technology and the piggyBac-mediated gene transfer system enables efficient isolation of stable transfectants in nonhuman mammalian cells. / Biotechnol. J. / 10 / 143 / 153 / 2015 / Online Journal

Matsuyama, J., Kinoshita-Kawano, S., Hayashi-Sakai, S., Mitomi, T., Sano-Asahito, T. / Severe impaction of the primary mandibular second molar accompanied by displacement of the permanent second premolar. / Case Rep. Dent. / Article ID: 582462 / / / 2015 / Online Journal

Takagishi, T., Oda, M., Kabura, M., Kurosawa, M., Tominaga, K., Urano, S., Ueda, Y.,Kobayashi, K., Kobayashi, T., Sakurai, J., Terao, Y., Nagahama, M. / Clostridium perfringens alpha-toxin induces GM1a clustering and TrkA phosphorylation in the host cell membrane. / PLoS one / Article ID: e0120497 / / / 2015 / Online Journal

Inada, E., Saitoh, I., Yong, Y., Tomiyama, D., Murakami, D., Takemoto, Y., Morizono, K., Iwasaki, T., Yamasaki, Y. / Quantitative evaluation of toothbrush and arm-joint motion during tooth brushing / Clin. Oral Investig. / 19 / 1451 / 1462 / 2015 / Online Journal

Iguchi, H., Magara, J., Nakamura, Y., Tsujimura, T., Ito, K., Inoue, M. / Changes in jaw muscle activity and physical property of foods with different textures during chewing. / Physiol. Behav. / 152 / 217 / 224 / 2015 / Online Journal

Aida, S., Takeishi, R., Magara, J., Watanabe, M., Ito, K., Nakamura, Y., Tsujimura, T., Hayashi, H., Inoue, M. / Peripheral and central control of swallowing initiation in healthy humans. / Physiol. Behav. / 151 / 404 / 411 / 2015 / Online Journal

Tsuji, K.,Tsujimura, T., Magara, J., Sakai, S., Nakamura, Y., Inoue, M. / Changes in the frequency of swallowing during electrical stimulation of superior laryngeal nerve in rats. / Brain Res. Bull. / 111 / 53 / 61 / 2015 / Online Journal

Sato, M., Inada, E., Saitoh, I., Matsumoto, Y. / An efficient and convenient method for Mini Prep analysis of recombinant plasmids. / J. Biomed. Sci. Eng. / 7 / 105 / 107 / 2014 / Online Journal

Murakami, D., Inada, E., Saitoh, I., Takemoto, Y., Morizono, K., Kubota, N., Iwasaki, T., Yamasaki, Y. / Morphological differences of facial soft tissue contours from child to adult of Japanese males: a three-dimensional cross-sectional study. / Arch. Oral Biol. / 59 / 1391 / 1399 / 2014 / Online Journal

Iwasaki, T., Takemoto, Y., Inada, E., Sato, H., Suga, H., Saitoh, I., Kakuno, E., Kanomi, R., Yamasaki, Y. / The effect of rapid maxillary expansion on pharyngeal airway pressure during inspiration evaluated by computational fluid dynamics. / Int. J. of Pediatr. Otorhinolaryngol. / 78 / 1258 / 1264 / 2014 / Online Journal

Kuise, T., Noguchi, H., Tazawa, H., Kawai, T., Iwamuro, M., Saitoh, I., Usui-Kataoka, H., Watanabe, M., Noguchi, Y., Fujiwara, T. / Establishment of a pancreatic stem cell line from fibroblast-derived induced pluripotent stem cells. / BioMedical Engineering OnLine / 13 / 64 / 64 / 2014 / Online Journal

Iwasaki, T., Takemoto, Y., Inada, E., Sato, H., Saitoh, I., Kakuno, E., Kanomi, R., Yamasaki, Y. / Three-dimensional cone-beam computed tomography analysis of enlargement of the pharyngeal airway by the Herbst appliance. / Am. J. Orthod. Dentofacial Orthop. / 146 / 776 / 785 / 2014 / Online Journal

Kohjitani, A., Miyata, M., Iwase, Y., Ohno, S., Tohya, A., Manabe, Y., Hashiguchi, T., Sugiyama, K. / Associations between the autonomic nervous system and the second derivative of the finger photoplethysmogram indices. / J. Atheroscler. Thromb. / 21 / 501 / 508 / 2014 / Online Journal

Oda, M., Yamamoto, H., Shibutani, M., Nakano, M., Yabiku, K., Tarui, T., Kameyama, N., Shirakawa, D., Obayashi, S., Watanabe, N., Nakase, H., Suenaga, M., Matsunaga, Y., Nagahama, M., Takahashi, H., Imagawa, H., Kurosawa, M., Terao, Y., Nishizawa, M., Sakurai, J. / Vizantin inhibits endotoxin-mediated immune responses via the Toll-like receptor 4/MD-2 complex. / J. Immunol. / 193 / 4507 / 4514 / 2014 / Online Journal

Matsuyama J, Tanaka R, Iizawa F, Sano T, Kinoshita-Kawano S, Hayashi-Sakai S, Mitomi T / Clinical and radiographic findings and usefulness of computed tomographic assessment in two children with regional odontodysplasia. / Case Rep. Dent. / Article ID: 764393 / / / 2014 / Online Journal

Hayasaki, H., Saitoh, I., Nakakura-Ohshima, K., Hanasaki, M., Nogami, Y., Nakajima, T., Inada, E., Iwasaki, T., Iwase, Y., Sawami, T., Kawasaki, K., Murakami, N., Murakami, T., Kurosawa, M., Kimi, M., Kagoshima, A., Souda, M., Yamasaki, Y. / Tooth brushing for oral prophylaxis. / Japanese Dental Science Review / 50 / 69 / 77 / 2014 / Online Journal

Tosaka, Y., Nakakura-Ohshima, K., Murakami, N., Ishii, R., Saitoh, I., Iwase, Y., Yoshihara, A., Ohuchi, A., Hayasaki, H. / Analysis of tooth brushing cycles. / Clin. Oral Investig. / 18 / 2045 / 2053 / 2014 / Online Journal

Mitomi, T., Kawano, Y., Kinoshita-Kawano, S. / Effect of the antineoplastic agent busulfan on rat molar root development. / Arch. Oral Biol. / 59 / 47 / 59 / 2014 / Online Journal

de Sousa, SF., Kawasaki, K., Kawasaki, M., Volponi, AA., Gomez, RS., Gomes, CC., Sharpe, PT., Ohazama, A. / PKA regulatory subunit expression in tooth development. / Gene. Expr. Patterns / 15 / 46 / 51 / 2014 / Online Journal

Kawasaki, M., Porntaveetus, T., Kawasaki, K., Oommen, S., Otsuka-Tanaka, Y., Hishinuma, M., Nomoto, T., Maeda, T., Takubo, K., Suda, T., Sharpe, PT., Ohazama, A. / R-spondins/Lgrs expression in tooth development. / Dev. Dyn. / 243 / 844 / 851 / 2014 / Online Journal

Yamamoto, S., Taniguchi, H., Hayashi, H., Hori, K., Tsujimura, T., Nakamura, Y., Sato, H., Inoue, M. / How do tablet properties influence swallowing behaviors? / J. Pharm. Pharmacol. / 66 / 32 / 39 / 2014 / Online Journal

Sato, M., Inada, E., Saitoh, I., Matsumoto, Y. / An efficient and convenient method for MiniPrep analysis of recombinant plasmids. / Biomed. Sci. Eng. / 7 / 105 / 107 / 2014 / Online Journal

Inada, E., Saitoh, I., Kubota, N., Takemoto, Y., Hayasaki, H., Yamasaki, Y. / Relationship between nasal and skeletal landmarks on lateral cephalograms of adult. / Aust. J. Forensic. Sci. / 46 / 339 / 347 / 2014 / Online Journal

Khonsari, RH., Ohazama, A., Raouf, R., Kawasaki, M., Kawasaki, K., Porntaveetus, T., Ghafoor, S., Hammond, P., Suttie, M., Odri, GA., Sandford, RN., Wood, JN., Sharpe, PT. / Multiple postnatal craniofacial anomalies are characterized by conditional loss of polycystic kidney disease 2 (Pkd2). / Hum. Mol. Genet. / 22 / 1873 / 1885 / 2013 / Online Journal

Noguchi, H., Saitoh, I., Kataoka, H., Watanabe, M., Fujiwara, T. / Culture conditions for mouse pancreatic stem cells. / Cell Med. / 5 / 63 / 68 / 2013 / Online Journal

Kuise, T., Noguchi, H., Saitoh, I., Kataoka, H., Watanabe, M., Fujiwara, T. / Isolation efficiency of mouse pancreatic stem cells is age-dependent. / Cell Med. / 5 / 69 / 73 / 2013 / Online Journal

Katayama, A., Noguchi, H., Kuise, T., Nakatsuka, A., Hirota, D., Usui-Kataoka H., Kawai, T., Inoue, K., Imagawa, N., Saitoh, I., Noguchi, Y., Watanabe, M., Wada, J., Fujiwara, T. / Comparison of new preservation solution, HN-1, and University of Wisconsin solution in pancreas preservation for porcine islet isolation. / Cell Med. / 6 / 3 / 8 / 2013 / Online Journal

Kawai T, Noguchi H, Kuise T, Nakatsuka A, Katayama A, Imagawa N, Usui Kataoka H, Saitoh I, Noguchi Y, Watanabe M, Fujiwara T / Comparison of incubation solutions prior to islet purification in porcine islet isolation. / Cell Med. / 6 / 9 / 14 / 2013 / Online Journal

Murakami, T., Saitoh, I., Inada, E., Kurosawa, M., Iwase, Y., Noguchi, H., Terao, Y., Yamasaki, Y., Hayasaki, H., Sato, M. / STO feeder cells are useful for propagation of primarily cultured human deciduous dental pulp cells by eliminating contaminating bacteria and promoting cellular outgrowth. / Cell Med. / 6 / 75 / 81 / 2013 / Online Journal

Yamada-Ito, C., Saitoh, I., Yashiro, K., Inada, E., Maruyama, T., Takada, K., Hayasaki, H., Yamasaki, Y. / Smoothness of molar movement during gum chewing in children with primary dentition. / Cranio / 31 / 260 / 269 / 2013 / Online Journal

Kohjitani, A., Miyawaki, T., Miyawaki, S., Nakamura, N., Iwase, Y., Nishihara, K., Ohno, S., Shimada, M., Sugiyama, K. / Features of lateral cephalograms associated with difficult laryngoscopy in Japanese children undergoing oral and maxillofacial surgery. / Pediatr. Anesth. / 23 / 994 / 1001 / 2013 / Online Journal

Nakamichi, T., Kitahara, T., Iwase, Y., Hyakutake, H., Takahashi, I. / Three-dimensional dynamic evaluation of a posed smile in normal occlusion and Class II malocclusion. / Orthod. Waves / 72 / 131 / 141 / 2013 / Online Journal

Iwasaki, T., Saitoh, I., Takemoto, Y., Inada, E., Kakuno, E., Kanomi, R., Hayasaki, H., Yamasaki, Y. / Tongue posture improvement and pharyngeal airway enlargement as secondary effects of rapid maxillary expansion: A cone-beam computed tomography study. / Am. J. Orthod. Dentofacial Orthop. / 143 / 235 / 245 / 2013 / Online Journal

Arakaki, M., Egusa, H., Otsu, K., Saitoh, I., Miura, T., Harada, H. / Frontier of iPS cell research in dentistry (Review). / J. Oral Biosc. / 55 / 191 / 199 / 2013 / Online Journal

Sato, M., Inada, E., Saitoh, I., Ohtsuka, M., Nakamura, S., Sakurai, T., Watanabe, S. / Site-targeted non-viral gene delivery by direct DNA injection into the pancreatic parenchyma and subsequent in vivo electroporation in mice. / Biotechnol. J. / 8 / 1355 / 1361 / 2013 / Online Journal

Sato, M., Kubota, N., Inada, E., Saitoh, I. / Mosaic expression of pluripotency-related proteins Oct-3/4 and alkaline phosphatase in human pancreatic carcinoma cell lines. / Advanced Studies in Biology / 5 / 157 / 172 / 2013 / Online Journal

Hayashi, H., Hori, K., Taniguchi, H., Nakamura, Y., Tsujimura, T., Ono, T., Inoue, M. / Biomechanics of human tongue movement during bolus compression and swallowing. / J. Oral Sci. / 55 / 191 / 198 / 2013 / Online Journal

Nakamura, Y., Hatakeyama, A., Kitada, Y., Tsujimura, T., Taniguchi, H., Inoue, M. / Effects of pharyngeal water stimulation on swallowing behaviors in healthy humans. / Exp. Brain Res. / 230 / 197 / 205 / 2013 / Online Journal

Yamada, A., Kajii, Y., Sakai, S., Tsujimura, T., Nakamura, Y., Ariyasingheb, S., Magara, J., Inoue, M. / Effects of chewing and swallowing behavior on jaw opening reflex responses in freely feeding rabbits. / Neuroscience Letters / 535 / 73 / 77 / 2013 / Online Journal

Shiozawa, M., Taniguchi, H., Hayashi, H., Hori, K., Tsujimura, T., Nakamura, Y., Ito, K., Inoue, M. / Differences in chewing behavior during mastication of foods with different textures. / Journal of Texture Studies / 44 / 44 / 45 / 2013 / Online Journal

Sato, M., Kubota, N., Inada, E., Saitoh, I., Ohtsuka, M., Nakamura, S., Sakurai, T., Watanabe, S. / HeLa cells consist of two cell types, as evidenced by cytochemical staining for alkaline phosphatase activity: A possible model for cancer stem cell study. / Adv. Stem Cell / Article ID 208514 / / / 2013 / Online Journal

Hayashi-Sakai, S., Sakai, J., Sakamoto, M., Endo, H. / Determination of fracture toughness of human permanent and primary enamel using an indentation microfracture method. / J. Mater. Sci. Mater. Med. / 23 / 2047 / 2054 / 2012 / Online Journal

Sato, T., Yamaki, K., Ishida, N., Shoji, M., Sato, E., Abiko, Y., Hashimoto, K., Takeuchi, Y., Matsuyama, J., Shimauchi, H., Takahashi, N. / Rapid quantification of bacteria in infected root canals using fluorescence filter: A pilot study on its clinical application to the evaluation of the outcomes of endodontic treatment. / Int. J. Dent. / Article ID 172935 / / / 2012 / Online Journal

Sato T, Yamaki K, Ishida N, Hashimoto K, Takeuchi Y, Shoji M, Sato E, Matsuyama J, Shimauchi H, Takahashi N: / Cultivable anaerobic microbiota of infected root canals. / Int. J. Dent. / Article ID 609689 / / / 2012 / Online Journal

Iwase, Y., Kohjitani, A., Tohya, A., Sugiyama, K. / Preoperative autologous blood donation and acute normovolemic hemodilution affect intraoperative blood loss during sagittal split ramus osteotomy. / Transfus. Apher. Sci. / 46 / 245 / 251 / 2012 / Online Journal

Oommen, S., Francois, M., Kawasaki, M., Murrell, M., Kawasaki, K., Porntaveetus, T., Ghafoor, S., Young, NJ., Okamatsu, Y., McGrath, J., Koopman, P., Sharpe, PT., Ohazama, A. / Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function. / PLoS One / Article ID e43857 / / / 2012 / Online Journal

Oommen, S., Otsuka-Tanaka, Y., Imam, N., Kawasaki, M., Kawasaki, K., Jalani-Ghazani, F., Anderegg, A., Awatramani, R., Hindges, R., Sharpe, PT., Ohazama, A. / Distinct roles of microRNAs in epithelium and mesenchyme during tooth development. / Dev. Dyn. / 241 / 1465 / 1472 / 2012 / Online Journal

Kawasaki, K., Porntaveetus, T., Oommen, S., Ghafoor, S., Kawasaki, M., Otsuka-Tanaka, Y., Blackburn, J., Kessler, JA., Sharpe, PT., Ohazama, A. / Bmp signalling in filiform tongue papillae development. / Arch. Oral Biol. / 57 / 805 / 813 / 2012 / Online Journal

Blackburn J, Ohazama A, Kawasaki K, Otsuka-Tanaka Y, Liu B, Honda K, Rountree RB, Hu Y, Kawasaki M, Birchmeier W, Schmidt-Ullrich R, Kinoshita A, Schutte BC, Hammond NL, Dixon MJ, Sharpe PT /

The role of Irf6 in tooth epithelial invagination. / Dev. Biol. / 365 / 61 / 70 / 2012 / http://www.ncbi.nlm.nih.gov/pubmed/22366192 /

Iwasaki, T., Saitoh, I., Takemoto, Y., Inada, E.,Kanomi, R., Hayasaki, H., Yamasaki, Y. / Improvement of nasal airway ventilation after rapid maxillary expansion evaluated with computational fluid dynamics. / Am. J. Orthod. Dentofacial Orthop. / 141 / 269 / 278 / 2012 / Online Journal

Inada, E., Saitoh, I., Nakakura-Ohshima, K., Maruyama, T., Iwasaki, T., Murakami, D., Tanaka, M., Hayasaki, H., Yamasaki, Y. / Association between mouth opening and head stability with intake of different-size food pieces during realistic eating. / Arch. Oral. Biol. / 57 / 307 / 313 / 2012 / Online Journal

Sato, M., Akasaka, E., Saitoh, I., Ohtsuka, M., Watanabe, S. / Development of a technique for efficient gene transfer to antral follicular cells in the mouse ovary. / Syst. Biol. Reprod. Med. / 58 / 136 / 141 / 2012 / Online Journal

Saitoh, I., Sato, M., Iwase, Y., Inada, E., Nomura, T., Akasaka, E., Yamasaki, Y., Noguchi, H. / Generation of mouse STO feeder cell lines that confer resistance to several types of selective drugs. / Cell Med. / 3 / 97 / 102 / 2012 / Online Journal

Sato, M., Akasaka, E., Saitoh, I., Ohtsuka, M., Watanabe, S. / In vivo gene tranger in mouse premplantation embryos after intraoviductal injection of plasmid DNA and subsequent in vivo electroporation. / Syst. Biol. Reprod. Med. / 58 / 278 / 287 / 2012 / Online Journal

Ishikawa, Y., Ida-Yonemochi, H., Nakakura-Ohshima, K., Ohshima, H. / The relationship between cell proliferation and differentiation and mapping of putative dental pulp stem cells during mouse molar development by chasing BrdU-labeling. / Cell Tissue Res. / 348 / 95 / 107 / 2012 / Online Journal

Sato, T., Kenmotsu, S., Nakakura-Ohshima, K., Takahashi, N., Ohshima, H. / Pulpal responses to antimicrobials in the infected dental pulp of rat molars. / Arch. Histol. Cytol. / 73 / 165 / 175 / 2012 /

Kohjitani A, Miyata M, Iwase Y, Sugiyama K / Responses of the second derivative of the finger photoplethysmogram indices and hemodynamic parameters to anesthesia induction. / Hypertens. Res. / 35 / 166 / 172 / 2012 / Online Journal

Tsujimura, T., Tsuji, K., Ariyasinghe, S., Fukuhara, T., Yamada, A., Hayashi, H., Nakamura, Y., Iwata, K., Inoue, M. / Differential involvement of two cortical masticatory areas in modulation of the swallowing reflex in rats. / Neuroscience Letters / 528 / 159 / 164 / 2012 / Online Journal

Tsujimura, T., Yamada, A., Nakamura, Y., Fukuhara, T., Yamamura, K., Inoue, M. / The digastric muscle is less involved in pharyngeal swallowing in rabbits. / Dysphagia / 27 / 271 / 276 / 2012 / Online Journal

Tsukano, H., Taniguchi, H., Hori, K., Tsujimura, T., Nakamura, Y., Inoue, M. / Individual-dependent effects of pharyngeal electrical stimulation on swallowing in healthy humans. / Physiol. Behav. / 106 / 218 / 223 / 2012 / Online Journal

Inada, E., Saitoh, I., Hayasaki, H., Iwase, Y., Kubota, N., Fukami, A., Yamasaki, Y. / Comparison of normal permanent and primary dentition sagittal tooth-crown inclinations of Japanese females. / Cranio / 30 / 41 / 51 / 2012 / Online Journal






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