Academic Organization


http://www.dent.niigata-u.ac.jp/anesth/anesth.html




- Application ofpatient controlled sedation using propofol in dental practice
- Study of the development of new treatments for chronic pain in the orofacial area
- Clinical and experimental studies of the physiological and anatomical changes of the upper trachea in oral surgery
- Studies of th activation mechanism of the intrinsic descending inhibitory
- Studies on an new treatment for the dental psychosomatic disorder
- Study of neuropathic pain in the orrofacial area
- Peripheral nerve imaging utilizing nuclear magnetic resonance




kenji SeoeoProfessorschool of dentistry university dental hospital department of dental anesthesia
Makoto TerumitsuAssociate Professorschool of dentistry university dental hospital department of dental anesthesia
Yutaka TanakaLecturerschool of dentistry university dental hospital department of dental anesthesia
Tatsuru TsurumakiAssistant Professorschool of dentistry university dental hospital department of dental anesthesia
Kurata ShigenobuAssistant Professorschool of dentistry university dental hospital department of dental anesthesia
Hiroko KanemaruResidentschool of dentistry university dental hospital department of dental anesthesia
Hiroyuki YoshikawaResidentschool of dentistry university dental hospital department of dental anesthesia
Yuki KondoResidentschool of dentistry university dental hospital department of dental anesthesia
Maiko HasegawaResidentschool of dentistry university dental hospital department of dental anesthesia
Yumiko SatoResidentschool of dentistry university dental hospital department of dental anesthesia
Akiko Sudagraduateschool of dentistry university dental hospital department of dental anesthesia
Mikiko Hiraharagraduateschool of dentistry university dental hospital department of dental anesthesia
Yurie Yamadagraduateschool of dentistry university dental hospital department of dental anesthesia





B. J. Sessle, Ruth E Martin, Gregory M Murray, Yuji Masuda, Pentti Kempainer, Noriyuki Narita, Kenji Seo and Ramin Raouf / Cortical mechanisms controlling mastication and swallowing in the awake monkey. (Toshifumi Morimoto, Tokuzo Matsuya, Kenji Takada) Brain and Oral Functions, oral motor function and dysfunction / / ELSEVIER / / / Amsterdam /

Hu J W, Tsai C-M, Bakke M, Seo K, Tambeli C H, Vernon H, Bereiter D A , Sessle B J / Deep craniofacial pain: Involvement of trigeminal subnucleus candalis and its modulation.(Troels S. Jenser, Judith A. Turner, Zsuzanna Wiesenfeld-Hallin) / / Proceedings of the 8th World Congress on Pain / / IASP Press / Seattle / 1998 / 497 / 506 /



Masaki KOHNO, Kimihiko HANADA, Masataka TASHIRO, Tsuneo YOSHIDA, Susumu SHINGAKI, Genji SOMEYA / Fracture of the Mandible accompanied by Liver Trauma leading to Hemorrhagic Shock / Niigata Dental Journal / 19(1) / 53 / 58 / 1989 /

Masaki Kohno, Tamio Nakajima, Genji Someya / Effect of Maxillomandibular Fixation on Respiration / J Oral Maxillofacial Surgery / 51 / 992 / 996 / 1993 / Online Journal

Kenji Seo, Haruko Takayama, Yumi Araya, Katsuhiko Miura, Genji Someya / A case of sinus arrest caused by a maneuver of opening the mouth under general anesthesia / Anesthesia Progress / 41 / 17 / 18 / 1994 / Online Journal

Kenji Seo, Yumi Araya, Haruko Takayama, Katsuhiko Miura, Genji Someya / Electromagnetic Interference of External Temporary Pacemaker undergoing Maxillofacial and Neck Surgery / Jurnal of Anesthesia & Pain Control in Dentistry / 43(2) / 64 / 66 / 1996 / Online Journal

Genji SOMEYA, Ichirou SUZUKI, Yosihiro AMEMIYA, Ken SAITOH, and Hiroshi KISHI / Development of a Supporting System of the Visiting Dental Care for the Bedridden Elderly Person Using a Personal Computer Network among Regional Dental Society, Municipal Office and University Dental Hospital / Dentistry in Japan / 33 / 164 / 164 / 1996 /

Kenji Seo, KatsuHiko Miura, Yutaka Tanaka, Yumi Kobayashi and Genji Someya / Floating Debris in a Blood Pack Just after a Collection for Autologous Blood Transfusion / Jurnal of Clinical Anesthesia / 20(11) / 1687 / 1688 / 1996 /

Masahiro, Suzuki Shuichi, Nomura Shingo, Iwakata Naoyuki,Taguti Masaharu, Kobayasi Kazuhiro,Yamada Takahuhumi,Hayasi Masayosi,Hukushima Takehiko,Kubota Kuniko,Oshima Yutaka,Tanaka Masashi,Kono / Team Approach for TMD Patients in Our Hospital, Present Conditionand Future Considerations / Niigata Dental Journal / 27(2) / 59 / 63 / 1997 / Online Journal

Yutaka, Tanaka Mayumi, Miura Hiroshi, Matsui / Retrospective investigation of the medical emergency cases occurredat the Niigata University dental hospital in 8 years and on thepresent condition of our rescue system of emergency cases / Niigata Dental Journal / 28(1) / 55 / 56 / 1998 / Online Journal

Masahiro, Suzuki Shuichi, Nomura Shingo, Iwakata Naoyuki,Taguti Masaharu, Kobayasi Kazuhiro,Yamada Takahuhumi,Hayasi Masayosi,Hukushima Takehiko,Kubota Kuniko,Oshima Yutaka,Tanaka Masashi,Kono / Present Condition and Future Considerations of Team Approach for TMDPatients in Our Hospital : The Second report / Niigata Dental Journal / 29(2) / 129 / 137 / 1999 / Online Journal

Yutaka Tanaka,Kenji Seo, Genji Someya / The present condition of Clinic for Psychosomatic Dentistry / Niigata Dental Journal / 31(2) / 195 / 196 / 2001 / Online Journal

Yoshida Y, Toyosato A, Md.O.Islam, Koga T, Fujita S, Imai / Stimulation of plasma membrane Ca2+-pump ATPase of vascular smooth muscle by cGMP-dependent protein kinase: Functional reconstitution with purified proteins / Mol. Cell. Biochem / 190 / 157 / 167 / 1999 / Online Journal

Kenji Seo, Genji Someya / Postnatal development of central nociceptive mechanisms modulating jaw muscelk activity in the rat / Neuroscience letters / 288 / 131 / 134 / 2000 / Online Journal

Kenji Seo, Genji Someya, Yutaka Tanaka, Hiroshi Matsui, Akira Toyosato / Sevoflurane and Isoflurane reduce oxygen saturation in infants / Anesthesia / 47 / 3 / 7 / 2000 / Online Journal

Mayumi Miura, Hiroshi Matsui, Yutaka Tanaka, Kenji Seo, Genji Someya / Tooth extractions from the patients with Osler-Weber-Rendu disease / journal of Japanese Society of Dentistry for Medically Compromised Patient / 8(1) / 13 / 17 / 2000 /

Kenji Seo, James W. Hu, Brain E. Cairns and Genji Someya / Involvement of GABAA receptor in modulation of jaw muscle activity evoked by mustard oil application to the rat temporomandibular joint / Brain Research / 892 / 198 / 202 / 2001 / Online Journal

Seo, K., Fujiwara, N., Takeuchi, K., Maeda, T., Someya, G. / Optical imaging of excitation propagation evoked by stimulation to the trigeminal caudalis / NeuroReport / 12(18) / 3985 / 3988 / 2001 / Online Journal

Tambeli, C.H., Seo, K., Sessle, B.J., Hu, J.W. / Central mu opioid receptor mechanisms modulate mustard oil-evoked jaw muscle activity / Brain Research / 913 / 90 / 94 / 2001 / Online Journal

Yamazaki, Y., Maeda, T., Someya, G., Wakisaka, S. / Temporal and spatial distribution of Fos protein in the lumbar spinal dorsal horn neurons in the rat with chronic constriction injury to the sciatic nerve / Brain Research / 914(1-2) / 106 / 114 / 2001 / Online Journal

Kenji Seo, Naoshi Fujiwara, Brian E. Cairns, and Genji Someya / Male rats require testosterone to develop contralateral digastric muscle activity in response to noxious stimulation of the temporomandibular joint / Neuroscience Letters / 335 / 107 / 110 / 2002 / Online Journal

Kenji Seo, Naoshi Fujiwara, James W. Hu, Brian E. Cairns, and Genji Someya / Intrathecal administration of 5-HT3 receptor agonist modulates jaw muscle activity evoked by injection of mustard oil into the temporomandibular joint in the rat / Brain Research / 934 / 157 / 161 / 2002 / Online Journal

Tatsuru Tsurumaki, Osamu Muraoka, Tsuyoshi Yamaguchi and Higuchi Hiroshi / Neuropeptide Y-induced contraction and its desensitization through the neuropeptide Y receptor subtype in several rat veins.Journal of Cardiovascular Pharmacology 41(supplement 1) / Vascul Pharmacol / 39(6) / 23 / 27 / 2002 / Online Journal

Kenji Seo, Haruko Takayama, Yumi Araya, Katsuhiko Miura, Genji Someya / Hyperergia Induced by Carbamazepine in a Patient With Trigeminal Neuralgia / Journal of Japanese dental society of Anesthesiology / 21(2) / 417 / 421 / 1993 /

Kimihiko HANADA, Masaki KOHNO, Takeshi NAGAMINE, Susumu SHINGAKI, Tamio NAKAJIMA, Genji SOMEYA / Acute Anesthetic Toxicity with Continuous Central Excitation during Stellate Ganglion Block; Report of a Case / Journal of Japanese dental society of Anesthesiology / 18(3) / 525 / 530 / 1990 /

Genji SOMEYA, Shinya FUSE, Akira IBI, Tamio NAKAJIMA, Nobuyuki IMAI, and Yasushi OHASHI / Statistical Observation on Incidence of Nausea and Vomiting in Postoperative Period After Oral and Maxillo-facial Surgery / Journal of Japanese dental society of Anesthesiology / 20(2) / 287 / 294 / 1992 /

Haruko TAKAYAMA, Kenji SEO, Yumi ARAYA, Katsuhiko MIURA and Genji SOMEYA / A Case of Posttraumatic Pain Syndrome Relieved with Prostaglandin E1 Ointment / Journal of Japanese dental society of Anesthesiology / 21 (4) / 827 / 836 / 1993 /

Kenji Seo, Haruko Takayama, Yumi Araya, Katsuhiko Miura, Yutaka Tanaka, Yumi Kobayashi, Genji Someya, Masaki Kohno, and Tamio Nakajima / Retrospective Study of the Perioperrative Managgement of Uvulopalatopharyngoplasty for Sleep Apnea Syndrome / Journal of Japanese dental society of Anesthesiology / 22(3) / 511 / 517 / 1994 /

Kenji Seo, Haruko Takayama, Yumi Araya, Katsuhiko Miura, Yutaka Tanaka, Yumi Kobayashi, and Genji Someya / Usefulness of Propofol as Induction Agent for General Anesthesia Undergoing Oral and Maxillofasial Surgert / Journal of Japanese dental society of Anesthesiology / 22(4) / 637 / 648 / 1994 /

Akira TOYOSATO, Genji SOMEYA, Mikiko NAKAZAWA, and Shoichi IMAI / Relaxation of Isolated Noradrenaline-Contracted Rat Aorta with Nitroglycerin and Nitoprusside:Activation of Potassium Channels and Concentration of Noradrrenaline / Journal of Japanese dental society of Anesthesiology / 24(1) / 62 / 69 / 1996 /

Kenji SEO, Yutaka TANAKA, and Genji SOMEYA / A Case of Maxillary Chronic Pain Diagnsed by Drug Challenge Test and Improved by NMDA Receptor Antagonist / Journal of Japanese dental society of Anesthesiology / 28(1) / 87 / 92 / 2000 /

Masahiko SHIMADA, Takuya MIYAWAKI, Koji TAKADA, Toru MISAKI, Shuichiro OKA, Setsu YOSHIMURA, Takao AYUSE, Kumiko OI, Kenji SEO, Genji SOMEYA, Tatsuya ICHINOHE, Yuzuru KANEKO, Kiyoshi ICHIHARA, Hiromichi ITO and Masahiro UMINO / The Clinical Anesthetic Efficacy of 3% Mepivacaine in Infiltration and Block Anesthesia: A Comparative Double Blind Study with 2% Lidocaine Hydrochloride containing 1:80,000 Epinephrine / Journal of Japanese dental society of Anesthesiology / 30(1) / 48 / 61 / 2002 /

Kenji SEO, Yutaka TANAKA, Hiroshi MATSUI and Genji SOMEYA / Clinical Observations of Sensory Impairment and its Recovery in Trigeminal Nerve Injury Following Orthognathic Surgery / Journal of Japanese dental society of Anesthesiology / 30(1) / 69 / 81 / 2002 /

Akira TOYOSATO, Hiroshi MATSUI, Emiko KOITO, Yutaka TANAKA, Kenji SEO and Genji SOMEYA / A Case of Difficult Extubation of the Spiral Tube / Journal of Japanese dental society of Anesthesiology / 30(3) / 356 / 357 / 2002 /

Kenji Seo, Naoshi Fujiwara, Kiichi Takeuchi, Takeyasu Maeda and Genji Someya / Repetitive afferent stimulation propagates excitation in trigeminal caudalis / NeuroReport / 14 / 1321 / 1325 / 2003 /

Kenji Seo, Yutaka Tanaka, Hiroshi Matsui, Genji Someya / Clinical observations of sensory impairment and revovery in trigeminal nerve injury after orthognathic surgery / Dentistry in Japan / 40 / 124 / 128 / 2004 /

Kenji Seo, Yutaka Tanaka, Makoto Terumitsu, Genji Somey / How do Japanese patients express claims of mumbness as a postoperative complication of orthognathic surgery? / Dentistry in Japan / 41 / 124 / 129 / 2005 /

Kenji Seo, Naoshi Fujiwara, Kiichi Takeuchi, Takeyasu Maeda and Genji Someya / Postnatal Development of Excitation Propagation in the Trigeminal Subnucleus Caudalis Evoked by Afferent Stimulation in Mice / Neuroscience Research / / / / 2005 /

Megumi Aita, Kenji Seo, Naoshi Fujiwara, Ritsuo Takagi, and Takeyasu Maeda / Postnatal changes in the spatial distributions of substance P and neurokinin-1 receptors in the trigeminal subnucleus caudalis of mice / Developmental Brain Research / 155 / 33 / 41 / 2005 /

Kenji Seo, Yutaka Tanaka, Makoto Terumitsu, and Genji Someya / Characterization of different paresthesias following orthognathic surgery of the mandible / Journal of Oral and Maxillofacial surgery / 63 / 298 / 303 / 2005 /

Kenji Seo, Yutaka Tanaka, Makoto Terumitsu, and Genji Someya / Efficacy of steroid treatment on sensory impairment following orthognatic surgery / Journal of Oral and Maxillofacial surgery / 62 / 1192 / 1196 / 2004 /

Terumitsu M, Fujii Y, Suzuki K, Kwee IL, Nakada T / Human primary motor cortex shows hemispheric specialization for speech. / Neuroreport / 17(11) / 1091 / 1095 / 2006 /

Mayumi Ogawa, Misako Takamatsu, Manabu Okamoto, Hiroshi Baba, Kenji Seo, Naoshi Fujiwara / Iteration of high-frequency stimulation enhances long-lasting excitatory responses in the spinal dorsal horn of rats. Characterization by optical imaging of spinal propagation / Neuroscience Research / 57 / 467 / 472 / 2006 /

Piao H, Nagai S, Tsurumaki T, Niki T, Higuchi H. / Potentiation by neuropeptide Y of histamine H1 receptor-mediated contraction in rat blood vessels. / Vascul Pharmacol. / 46(4) / 260 / 270 / 2006 /

Tsurumaki T, Nagai S, Bo X, Toyosato A, Higuchi H. / Potentiation by neuropeptide Y of 5HT2A receptor-mediated contraction in porcine coronary artery. / Eur J Pharmacol. / 544(1-3) / 111 / 117 / 2006 /

Megumi Aita, Takeyasu Maeda, Kenji Seo, / The effect of neonatal capsaicin treatment on the CGRP- immunoreaction in the trigeminal subnucleus caudalis of mice / Biomedical Research / 29 / 33 / 42 / 2007 /

Nagai S, Tsurumaki T, Abe H, Higuchi H. / Functional serotonin and histamine receptor subtypes in porcine ciliary artery in comparison with middle cerebral artery. / Eur J Pharmacol. / 570(1-3) / 159 / 166 / 2007 /

Akira Toyosato, Shuichi Nomura, Atsuko Igarashi, Naoko Ii, Akiko Nomura / A relation between the Piezoelectric Pulse Tranceducer waveforms and food bolus passage during pharyngeal phase. / Prosthodont Res Pract . / 6(4) / 272 / 275 / 2007 /

Kenji Seo, Yuji Inada, Makoto Terumitsu, Tatsuo Nakamura, Katsuhiro Horiuchi and Ikuhisa Inada, Genji Someya. / One year outcome of a damaged lingual nerve repair using a PGA-Collagen tube: A Case Report, / Journal of Oral and Maxillofac Surg. / 66(7) / 1478 / 1481 / 2008 /

Hiroyuki Seino, Kenji Seo, Takeyasu Maeda, Genji Someya / Behavioural and histological observations of sensory impairment caused by tight ligation of the trigeminal nerve in mice / J Neuroscience Methods / 181 / 67 / 72 / 2009 /

Terumitsu M., Ikeda K., Kwee I. L., Nakada T. / articipation of primary motor cortex area 4a in complex sensory processing: 3T fMRI study / NeuroReport / 20(7) / 679 / 683 / 2009 /

Kenji Seo, Hiroyuki Seino, Hiroyuki Yoshikawa, Andrey B. Petrenko,Hiroshi Baba, Naoshi Fujiwara, Genji Someya, Yoshiro Kawano, Takeyasu Maeda,Masato Matsuda, Takashi Kanematsu, Masato Hirata / Genetic reduction of GABAA receptor γ2 subunit expression potentiates the immobilizing action of isoflurane / Neuroscience Letters / 472 / 1 / 4 / 2010 /

Terumitsu M, Seo K, Matsuzawa H, Yamazaki M, Kwee I L, Nakada T. / Morphologic evaluation of the inferior alveolar nerve in patients with sensory disorders by high-resolution 3D volume rendering MR neurography on a 3.0-T system / Oral Surg Oral Med Oral Pathol Oral Radiol Endod / 111 / 95 / 102 / 2010 /

Yoneoka Y, Isogawa M, Terumitsu M, Matsuzawa H, Fujii Y / Insidious extension of pituitary prolactinoma: two can't-miss findings depicted on a 3.0-T MR system / J Neuroimaging. / 20(3) / 267 / 271 / 2010 /

Terumitsu M, Seo K, Matsuzawa H, Yamazaki M, Kwee I L, Nakada T / Morphologic evaluation of the inferior alveolar nerve in patients with sensory disorders by high-resolution 3D volume rendering magnetic neurography on a 3.0-T system. / Oral Surg Oral Med Oral Pathol Oral Radiol Endod / 111 / 95 / 102 / 2011 /

Terumitsu M, Nakada T. / Letters to Editor. Morphologic evaluation of the inferior alveolar nerve in patients with sensory disorders by high-resolution 3D volume rendering magnetic neurography on a 3.0-T system. / Oral Surg Oral Med Oral Pathol Oral Radiol Endod / 112 / 289 / 289 / 2011 /

Kenji Seo, Makoto Terumistu, Yutaka Tanaka, Tatsuru Tsurumaki, Shigenobu Kurata, Hitoshi Matsuzawa, Ristuo Takagi / Preoperative evaluation of spatial relationship between inferior alveolar nerve and fibro-osseous lesion by high resolution MR neurography on 3.0T system / Journal of Oral and Maxilofacial Surgery / 70(2) / 119 / 123 / 2012 /

Zakir HM, Mostafeezur RM, Suzuki A, Hitomi S, Suzuki I, Maeda T, Seo K, Yamada Y, Yamamura K, Lev S, Binstok AM, Iwata K, Kitagawa J / Expression of TRPV1 channels after nerve injury provides an essential delivery tool for neuropathic pain attenuation / Plos One / 7(9) / e44023 / / 2012 /

Kodama Y, Seo K, Hayashi T, Kobayashi T, Niwano M, Koyama T, Murayama M, Takagi R. / Orofacial pain related to traumatic neuroma in a patient with multiple TMJ operations. / Cranio / 30(3) / 183 / 187 / 2012 /

Seo K, Inada Y, Terumitsu M, Nakamura T, Shigeno K, Tanaka Y, Tsurumaki T, Kurata S, Matsuzawa H. / Protracted delay in taste sensation recovery after surgical lingual nerve repair: a case report. / J Med Case Rep. / 18;7(1) / 77 / 77 / 2013 /

Terumitsu M, Matsuzawa H, Seo K, Nakada T. / Evaluating Fine Structure of the Injured Trigeminal Nerve and Tissue Using a 3.0-T System. / Journal of the Peripheral Nervous System / 18 (supplement) / 115 / 115 / 2013 /

Nishikawa T, Okamoto K, Matsuzawa H, Terumitsu M, Nakada T, Fujii Y / Detectability of Neural Tracts and Nuclei in the Brainstem Utilizing 3DAC-PROPELLER. / J Neuroimaging 2013 / 111(1) / 95 / 102 / 2013 /

Kenji Seo, Yuji Inada, Makoto Terumitsu, Tatsuo Nakamura, Keiji Shigeno, Yutaka Tanaka, Tatsuru Tsurumaki, Shigenobu Kurata, Hitoshi Matsuzawa. / Protracted delay in taste sensation recovery after surgical lingual nerve repair: a case report / Journal of Medical Case Reports / 7(1) / 77 / 77 / 2013 /

Nishikawa T, Okamoto K, Matsuzawa H, Terumitsu M, Nakada T, Fujii Y. / Detectability of Neural Tracts and Nuclei in the Brainstem Utilizing 3DAC-PROPELLER. / J Neuroimaging / 24(3) / 238 / 244 / 2013 /

Terumitsu M, Matsuzawa H, Seo K, Nakada T. / Evaluating Fine Structure of the Injured Trigeminal Nerve and Tissue Using a 3.0-T System. / Journal of the Peripheral Nervous System / 18(sppl) / 115 / 115 / 2013 /






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