Academic Organization

Reconstructive Surgery for Oral and Maxillofacial Region

http://www.dent.niigata-u.ac.jp/surgery1/




- Diagnosis and treatment of head and neck cancer
- Surgical-orthodontic treatment of jaw deformities
- Psychological evaluation of patients with oral and maxillofacial region
- Diagnosis and treatment of sleep-disordered breathing
- Experimental and clinical study of tissue-engineering using mesenchymal stem cells and their secretomes
- Distraction osteogenesis and bone grafting
- Oral and maxillofacial implants for reconstructed jaw bones
- Experimental and clinical study of tooth transplantation




Tadaharu KOBAYASHIProfessorfirst department of oral and maxillofacial surgery, faculty of dentistry
Wataru KATAGIRIAssociate Professorfirst department of oral and maxillofacial surgery, faculty of dentistry
Ichiro SUZUKIAssociate Professorfirst department of oral and maxillofacial surgery, faculty of dentistry
Akinori FUNAYAMALecturerfirst department of oral and maxillofacial surgery, faculty of dentistry
Kanae NIIMILecturerfirst department of oral and maxillofacial surgery, faculty of dentistry
Daichi HASEBEAssistant Professorfirst department of oral and maxillofacial surgery, faculty of dentistry
Toshihiko MIKAMIAssistant Professorfirst department of oral and maxillofacial surgery, faculty of dentistry
Hidenobu SAKUMAAssistant Professorfirst department of oral and maxillofacial surgery, faculty of dentistry
Naoaki SAITOAssistant Professorfirst department of oral and maxillofacial surgery, faculty of dentistry
Shohei KANEMARUResidentfirst department of oral and maxillofacial surgery, faculty of dentistry
Daisuke SAITOResidentfirst department of oral and maxillofacial surgery, faculty of dentistry
Daisuke SUDAResident
Ryoko TAKEUCHIGraduate Studentfirst department of oral and maxillofacial surgery, faculty of dentistry
Naoko OGINOGraduate Studentfirst department of oral and maxillofacial surgery, faculty of dentistry
Satoshi ENDOGraduate Studentfirst department of oral and maxillofacial surgery, faculty of dentistry
Kenta HAGAGraduate Studentfirst department of oral and maxillofacial surgery, faculty of dentistry
Masami KAWAHARADAGraduate Studentfirst department of oral and maxillofacial surgery, faculty of dentistry
Akihiko NAKAMURAGraduate Studentfirst department of oral and maxillofacial surgery, faculty of dentistry
Eri ASAMIGraduate Studentfirst department of oral and maxillofacial surgery, faculty of dentistry
Taichi HARAGraduate Studentfirst department of oral and maxillofacial surgery, faculty of dentistry
Norio ONODAGraduate Studentfirst department of oral and maxillofacial surgery, faculty of dentistry
Yoshinoti INABAGraduate Studentfirst department of oral and maxillofacial surgery, faculty of dentistry
Kiyoshi IWANOResidentfirst department of oral and maxillofacial surgery, faculty of dentistry
Yukiko ONOResidentfirst department of oral and maxillofacial surgery, faculty of dentistry
Gen AIKAWAAffiliated hospitalfirst department of oral and maxillofacial surgery, faculty of dentistry
Yusuke KATOAffiliated hospital
Gentaro TAKEUCHIAffiliated hospitalfirst department of oral and maxillofacial surgery, faculty of dentistry
Kana KURABEAffiliated hospitalfirst department of oral and maxillofacial surgery, faculty of dentistry





Hibi H, Katagiri W, et.al / Tissue-Engineered Bone and Cell-Conditioned Media / Ole T. Jensen / The Sinus Bone Graft / 3rd Ed. / QUINTESSENCE PUBLISHING / IL, USA / 2018 / 235 / 243 /

Izumi K, Kato H, Feinberg SE / 3D reconstruction of oral mucosa; Tissue engineering strategies / Vishwakarma A, Sharpe P, Shi S, Wang X-P, Ramalingam M / Stem Cell Biology and Tissue Engineering in Dental Science / 1st ed. / Academic Press/Elsevier / Waltham, MA, USA / 2012 /

Izumi K, Feinberg SE / Skin and Oral Mucosal Substitutes. / Buckley,MJ, Keller JC / Oral and Maxillofacial Clinics of North America, Volume 14 / 1st ed. / W.B.Saunders / PA, USA / 2001 / 1 / 11 /



Ryoko Takeuchi, Wataru Katagiri, Satoshi Endo, Tadaharu Kobayashi / Exosomes from conditioned media of bone marrow-derived mesenchymal stem cells promote bone regeneration by enhancing angiogenesis / PLOS ONE / 14 / e0225472 / / 2019 / Online Journal

Shimizu S, Tsuchiya S, Hirakawa A, Kato K, Ando M, Mizuno M, Osugi M, Okabe K, Katagiri W, Hibi H. / Design of a Randomized Controlled Clinical Study of tissue-engineered osteogenic materials using bone marrow-derived mesenchymal cells for Maxillomandibular bone defects in Japan: the TEOM study protocol. / BMC Oral Health / 19 / 69 / / 2019 / Online Journal

Kuryu M, Niimi K, Gotoh H, Shimizu T, Kobayashi T. / Assessment of the oral health-related quality of life and the health-related quality of life of patients with stomatological diseases. / Oral Sci Int / 16 / 147 / 154 / 2019 /

Tsunekia M, Maruyama S, Yamazakib M, Niimi K, Kobayashi T, Nishiyama H, Hayshi T, Tanuma J / Masseter muscle hypertrophy: A case report. / Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology / 31 / 428 / 431 / 2019 /

Hoshikawa E, Sato T, Kimori Y, Suzuki A, Haga K, Kato H, Tabeta K, Nanba D, Izumi K. / Noninvasive measurement of cell/colony motion using image analysis methods to evaluate the proliferative capacity of oral keratinocytes as a tool for quality control in regenerative medicine. / Journal of Tissue Engineering / 10 / 1 / 12 / 2019 / Online Journal

Ishiyama H, Hasebe D, Sato K, Sakamoto Y, Furuhashi A, Komori E, Yuasa H / The Efficacy of Device Designs (Mono-block or Bi-block) in Oral Appliance Therapy for Obstructive Sleep Apnea Patients: A Systematic Review and Meta-Analysis /  Int J Environ Res Public Health / / 16 / 17 / 2019 /

Sakamoto Y, Furuhashi A, Komori E, Ishiyama H, Hasebe D, Sato K, Yuasa H. / The Most Effective Amount of Forward Movement for Oral Appliances for Obstructive Sleep Apnea: A Systematic Review /  Int J Environ Res Public Health / / 16 / 18 / 2019 /

Saito N, Funayama A, Arai Y, Suda D, Takata Y, Kobayashi T / Vertical distraction osteogenesis of a reconstructed mandible with a free vascularized fibula flap: a report of two cases /  Maxillofac Plast Reconstr Surg. / 40 / 1 / 8 / 2018 / Online Journal

Kawasaki M, Kawasaki K, Meguro F, Yamada A, Ishikawa R, Porntaveetus T, Blackburn J, Otsuka-Tanaka Y, Saito N, Ota MS, Sharpe PT, Kessler JA, Herz J, Cobourne MT, Maeda T, Ohazama A /  Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms /  PLOS ONE / 13 / e0204126 / / 2018 / Online Journal

Nakamura K, Kaya H, Kobayashi T, Saito N, Yamada M / Bulleidia extructa and Actinomyces israelii infections in a patient with brain abscess / Neurological sciences / 39 / 1641 / 1642 / 2018 / Online Journal

Niimi K, Shingaki S, Funayama A, Mikami T, Nishiyam H, Hayashi T, Yamazaki M, Maruyama S, Saku T, Kobayashi T / Oral and maxillofacial manifestations of methotrexate-associated lymphoproliferative disorder in a patient with rheumatoid arthritis: Report of a case / J Oral Maxillofac Surg Med Pathol / 31 / 86 / 93 / 2018 /

Ogata K, Matsumura M, Moriyama M, Katagiri W, Hibi H, Nakamura S. / Cytokine mixtures mimicking secretomes from mesenchymal stem cells improve medication-related osteonecrosis of the jaw in a rat model. / JBMR plus / 2 / 69 / 80 / 2018 /

  Ogata K, Osugi M, Kawai T, Wakayama Y, Sakaguchi K, Nakamura S, Katagiri W. / Secretomes of mesenchymal stem cells induce bone regeneration by accelerating migration of stem cells. / J Oral Maxillofac Surg Med Pathol / 30 / 445 / 451 / 2018 /

Tsuruta T, Sakai K, Watanabe J, Katagiri W, Hibi H / Dental pulp-derived stem cell conditioned medium to regenerate peripheral nerves in a novel animal model of dysphagia. / PLOS ONE / 13 / e0208938 / / 2018 / Online Journal

Asai Y, Hasebe D, Saito I, Kobayashi T / Changes of nasal and oronasopharyngeal airway morphologies and nasal respiratory function following orthognathic surgery. / J Oral Maxillofac Surg Med Pathol, In press /

Mikami T, Kato Y, Kojima T, Abe T, Maruyama S, Nishiyama H, Hayashi T, Kobayashi T / An unusual and difficult diagnosis of synovial chondromatosis: a case report. / J Oral Maxillofac Surg Med Pathol / 30 / 422 / 427 / 2018 /

Uchikawa E, Yoshizawa M, Funayama A, Mikami T, Kobayashi T / Recurrent congenital double upper lip: A case report. / J Oral Maxillofac Surg Med Pathol, In press /

Saito N, Kato H, Akiba H, Hara Y, Kojima T, Yoshizawa M, Ohazama A, Maeda T, Kobayashi T, Izumi K / Application of Hypoxic Exposure Combined with Osteogenic Induction for the Enhancement of Multiple Osteoinductive Capabilities in Rat Mesenchymal Cells. / Open J Stomatol / 8 / 53 / 69 / 2018 /

Katagiri W, Watanebe J, Toyama N, Osugi M, Sakaguchi K, Hibi H / Clinical study of bone regeneration by conditioned medium from mesenchymal stem cells after maxillary sinus floor elevation. / Implant Dent / 36 / 607 / 612 / 2017 /

Katagiri W, Kawai T, Osugi M, Sugimura-Wakayama Y, Sakaguchi K, Kojima T, Kobayashi T / Angiogenesis in newly regenerated bone by secretomes of human mesenchymal stem cells. / Maxillofac Plast Reconstr Surg / 39 / 8 / 8 / 2017 /

Suda D, Ohazama A, Maeda T, Kobayashi T / The effect of bone mass and architecture on mandibular condyle after mandibular distraction. / Oral Surg Oral Med Oral Pathol Oral Radiol / 124 / 339 / 347 / 2017 /

Funayama A, Kojima T, Yoshizawa M, Mikami T, Kanemaru S, Niimi K, Oda Y, Kato Y, Kobayashi T / A simple technique for repositioning of the mandible by a surgical guide prepared using a three-dimensional model after segmental mandibulectomy. / Maxillofacial Plastic and Reconstructive Surgery / 39 / 16 / 16 / 2017 /

Suda D, Takatsuji H, Saito N, Funayama A, Niimi K, Kobayashi T / Septic arthritis of the temporomandibular joint without an apparent source of infection: a case report. / Open J Stomatol / 7 / 242 / 249 / 2017 /

Niimi K, Yoshizawa M, Koyama T, Funayama A, Mikami T, Kobayashi T / An Experimental Study on the Effects of Platelet Rich Plasma on the Wound Healing of Tooth Extraction-Related Bone Defects. / Open J Stomatol / 7 / 327 / 335 / 2017 /

Katagiri W, Sakaguchi K, Kawai T, Wakayama Y, Osugi M, Hibi H / A defined mix of cytokines mimics conditioned medium from cultures of bone marrow-derived mesenchymal stem cells and elicits bone regeneration. / Cell Prolif / 50 / / / 2017 /

Saito D, Mikami T, Oda Y, Hasebe D, Nishiyama H, Saito I, Kobayashi T / Relationships among maxillofacial morphologies, bone properties, and bone metabolic markers in patients with jaw deformities. / Int J Oral Maxillofac Surg / 45 / 985 / 991 / 2016 /

Funayama A, Mikami T, Niimi K, Kano H, Nikkuni Y, Yamazaki M, Kobayashi T / Electron Probe Microanalysis of Exogenous Pigmentation of Oral Mucosa Originating from Dental Alloy / Open Journal of Stomatology / 6 / 120 / 126 / 2016 /

Nomura T, Powers MP, Katz JL, Ejiri S, Kobayashi T / Histomorphometric Comparison of Transmandibular Implant and Titanium Implant. / J Long Term Eff Med Implants / 26 / 209 / 215 / 2016 /

Avila-Ortiz G, Bartold PM, Giannobile W, Katagiri W, Nares S, Rios H, Spagnoli D, Wikesjö UM / Biologics and Cell Therapy Tissue Engineering Approaches for the Management of the Edentulous Maxilla / Int J Oral Maxillofac Implants / 31 / 121 / 164 / 2016 /

Yoshizawa M, Niimi K, Sugai T, Aoyama S, Koyama T, Inoue M, Kobayashi T / Invasive cervical resorption of autotransplanted tooth with complete root formation. / JSM Dent / 4 / 1066 / / 2016 /

Kurabe K, Kojima T, Kato Y, Saito I, Kobayashi T / Impact of orthognathic surgery on oral health-related quality of life in patients with jaw deformities. / Int J Oral Maxillofac Surg / 45 / 1513 / 1516 / 2016 /

Uenoyama A, Kakizaki I, Shiomi A, Saito N, Hara Y, Saito T, Ohnuki H, Kato H, Takagi R, Maeda T, Izumi K / Effects of C-xylopyranoside derivative on epithelial regeneration in an in vitro 3D oral mucosa model. / Biosci Biotechnol Biochem / 80 / 1344 / 1355 / 2016 /

Mikami T, Maruyama S, Abé T, Kobayashi T, Yamazaki M, Funayama A, Shingaki S, Kobayashi T, Jun C, Saku T / Keratin 17 is co-expressed with 14-3-3 sigma in oral carcinoma in situ and squamous cell carcinoma and modulates cell proliferation and size but not cell migration. / Virchows Arch / 466 / 559 / 569 / 2015 /

Takatsuji H, Kobayashi T, Kojima T, Hasebe D, Izumi N, Saito I, Saito C / Effects of orthognathic surgery on psychological status of patients with jaw deformities / Int J Oral Maxillofac Surg / 44 / 1125 / 1130 / 2015 /

Takeuchi G, Kobayashi T, Hasebe D, Funayama A, Mikami T, Saito C / Changes in maximum lip closing force following orthognathic surgery in patients with jaw deformities. / J Oral Maxillofac Surg Med Pathol / 27 / 465 / 469 / 2015 /

Nomura T, Kobayashi T, Shingaki S, Saito C / A case of chondrosarcoma arising in the temporomandibular joint / Case Reports in Otolaryngology / / / / 2015 / Online Journal

Yoshiba N, Yoshiba K, Ohkura N, Takei E, Edanami N, Oda Y, Hosoya A, Nakamura H, Okiji T / Correlation Between Fibrillin-1 Degradation and mRNA Downregulation and Myofibroblasts Differentiation in Cultured Human Dental Pulp Tissue / J Histochem Cytochem / 63 / 438 / 448 / 2015 /

Nomura T, Shingaki S, Kobayashi T, Suzuki I, Saito C / Multi-factorial functional analysis of the patients with reconstruction for oral carcinoma / Open Journal of Stomatology / 5 / 63 / 71 / 2015 /

Nomura T, Shingaki S, Kobayashi T, Suzuki I, Saito C / Multi-factorial functional analysis of the patients with reconstruction for oral carcinoma / Open Journal of Stomatology / 5 / 63 / 71 / 2015 /

Miyota S, Kobayashi T, Abé T, Miyajima H, Nagata M, Hoshina H, Kobayashi T, Takagi R, Saku T / Intraoperative assessment of surgical margins of oral squamous cell carcinoma using frozen sections: a practical clinicopathological management for recurrences. / Biomed Res Int / / / / 2014 / Online Journal

Sakagami N, Kobayashi T, Nozawa-Inoue K, Oda K, Kojima T, Maeda T, Saito C / A histological study of deformation of the mandibular condyle caused by distraction in a rat model / Oral Surg Oral Med Oral Pathol Oral Radiol Endod / 118 / 284 / 294 / 2014 /

Uesugi T, Kobayashi T, Hasebe D, Tanaka R, Ike M, Saito C / Effects of orthognathic surgery on pharyngeal airway and respiratory function during sleep in patients with mandibular prognathism / Int J Oral Maxillofac Surg / 43 / 1082 / 1090 / 2014 /

Shingaki S, Kanemaru S, Oda Y, Niimi K, Mikami T, Funayama A, Saito C / Distant metastasis and survival of adenoid cystic carcinoma after definitive treatment. / J Oral Maxillofac Surg Med Pathol / 26 / 312 / 316 / 2014 /

Abé T, Maruyama S, Yamazaki M, Essa A, Babkair H, Mikami T, Shingaki S, Kobayashi T, Hayashi T, Cheng J, Saku T / Intramuscular keratocyst as a soft tissue counterpart of keratocystic odontogenic tumor: differential diagnosis by immunohistochemistry. / Hum Pathol / 45 / 110 / 118 / 2014 /

Nagata M, Noman AA, Suzuki K, Kurita H, Ohnishi M, Ohyama T, Kitamura N, Kobayashi T, Uematsu K, Takahashi K, Kodama N, Kawase T, Hoshina H, Ikeda N, Shingaki S, Takagi R / ITGA3 and ITGB4 expression biomarkers estimate the risks of locoregional and hematogenous dissemination of oral squamous cell carcinoma. / BMC Cancer / 13 / 410 / 410 / 2013 /

Kojima T, Hasegawa T, Freitas PHL, Yamamoto T, Sasaki M, Horiuchi K, Hongo H, Yamada T, Sakagami N, Saito N, Yoshizawa M, Kobayashi T, Maeda T, Saito C, Amizuka N / Histochemical aspects of the vascular invasion at the erosion zone of the epiphyseal cartilage in MMP-9-deficient mice. / Biomed Res / 34 / 119 / 128 / 2013 /

Tsuneki M, Maruyama S, Yamazaki M, Abe T, Adeola HA, Cheng J, Nishiyama H, Hayashi T, Kobayashi T, Takagi R, Funayama A, Saito C, Saku T / Inflammatory histopathogenesis of nasopalatine duct cyst: a clinicopathological study of 41 cases. / Oral Dis / 19 / 415 / 424 / 2013 /

Yoshizawa M, Koyama T, Izumi N, Niimi K, Ono Y, Ajima H, Funayama A, Mikami T, Kobayashi T, Ono K, Takagi R, Saito C / Autotransplantation or replantation of cryopreserved teeth: a case series and literature review. / Dental Traumatol / 30 / 71 / 75 / 2013 /

Kobayashi T, Funayama A, Hasebe D, Kato Y, Yoshizawa M, Saito C / Changes in overnight arterial oxygen saturation after mandibular setback. / Br J Oral Maxillofacial Surg. / 51 / 312 / 318 / 2013 /

Yoshiba N, Yoshiba K, Ohkura N, Hosoya A, Shigetani Y, Yamanaka Y, Izumi N, Nakamura H, Okiji T / Expressional alterations of fibrillin-1 during wound healing of human dental pulp / J Endod / 38 / 177 / 184 / 2012 /

Kato K, Kobayashi T, Kato Y, Takata Y, Yoshizawa M, Saito C / Changes in masticatory functions after surgical orthognathic treatment in patients with jaw deformities: Efficacy of masticatory exercise using chewing gum. / J Oral Maxillofac Surg Med Pathol. / 24 / 147 / 151 / 2012 /

Yoshizawa M, Koyama T, Kojima T, Kato H, Ono Y, Saito C / Keratinocytes of tissue-engineered human oral mucosa promote re-epithelialization after intraoral grafting in athymic mice. / J Oral Maxillofac Surg / 70 / 1199 / 214 / 2012 /

Funayama A, Maruyama S, Yamazaki M, Al-Eryani K, Shingaki S, Saito C, Cheng J, Saku T / Intraepithelially entrapped blood vessels in oralcarcinomain-situ. / Virchows Arch. / 460 / 473 / 480 / 2012 /

Ali MN, Kobayashi T, Tanaka M, Ohshima H, Ejiri S, Saito C / Effects of Intermittent Parathyroid Hormone Treatment on New Bone Formation during Distraction Osteogenesis in the Rat Mandible. / Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology / 114 / e36 / e42 / 2012 /

Kobayashi T, Maruyama S, Abé T, Cheng J, Takagi R, Saito C, Saku T / Keratin 10-positive orthokeratotic dysplasia: a new leucoplakia-type precancerous entity of the oral mucosa. / Histopathology. / 61 / 910 / 920 / 2012 /

Ohnuki H, Izumi K, Terada M, Saito T, Kato H, Suzuki A, Kawano Y, Nozawa-Inoue K, Takagi R, Maeda T / Zoledronic acid induces S-phase arrest via a DNA damage response in normal human oral keratinocytes. / Arch Oral Biol. / 57 / 906 / 917 / 2012 /

Aoyama S, Yoshizawa M, Niimi K, Sugai T, Kitamura N, Saito C / Prognostic factors for autotransplantation of teeth with complete root formation. / Oral Surg Oral Med Oral Pathol Oral Radiol Endod. / 114(5S) / S216 / S228 / 2012 /

Terada M, Izumi K, Ohnuki H, Saito T, Kato H, Yamamoto M, Kawano Y, Nozawa-Inoue K, Kashiwazaki H, Ikoma T, Tanaka J, Maeda T / Construction and characterization of a tissue-engineered oral mucosa equivalent based on a chitosan-fish scale collagen composite. / J Biomed Mater Res B Appl Biomater. / 100 / 1792 / 1802 / 2012 /

Arasawa M, Oda Y, Kobayashi T, Uoshima K, Nishiyama H, Hoshina H, Saito C / Evaluation of bone volume changes after sinus floor augmentation with autogenous bone grafts. / Int J Oral Maxillofac Surg. / 41 / 853 / 857 / 2012 /

Iwamoto T, Takata Y, Kitamura N, Hasebe D, Kobayashi T, Saito C / Prognostic predictors on the efficacy of oral appliance therapy for obstructive sleep apnea syndrome. / Open Journal of Stomatology. / 2 / 210 / 221 / 2012 /

Kobayashi T, Izumi N, Kojima T, Sakagami N, Saito I, Saito C / Progressive condylar resorption after mandibular advancement. / Br J Oral Maxillofac Surg. / 50 / 176 / 180 / 2012 /

Sato H, Kobayashi T, Takatsuji H, Funayama A, Mikami T, Saito C / Effect of orthognathic surgery on middle ear condition. / Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology / 24 / 75 / 79 / 2012 /

Nagata M, Hoshina H, Li M, Arasawa M, Uematsu K, Ogawa S, Yamada K, Kawase T, Suzuki K, Ogose A, Fuse I, Okuda K, Uoshima K, Nakata K, Yoshie H, Takagi R. / A clinical study of alveolar bone tissue engineering with cultured autogenous periosteal cells: Coordinated activation of bone formation and resorption. / Bone. / 50 / 1123 / 1129 / 2012 /

Yoshiba N, Yoshiba K, Ohkura N, Hosoya A, Shigetani Y, Yamanaka Y, Izumi N, Nakamura H, Okiji T / Expressional Alterations of Fibrillin-1 during Wound Healing of Human Dental Pulp / Journal of Endodontics / 38 / 177 / 184 / 2012 /

Yoshizawa M, Koyama T, Kojima T, Kato H, Ono Y, Saito C / Keratinocytes of tissue-engineered human oral mucosa promote re-epithelialization after intraoral grafting in athymic mice. / J Oral Maxillofac Surg / 70 / 1199 / 1214 / 2012 / Online Journal

Funayama A, Cheng J, Maruyama S, Yamazaki M, Kobayashi T, Syafriadi M, Kundu S, Shingaki S, Saito C, Saku T / Enhanced Expression of Podoplanin in Oral Carcinomas in situ and Squamous Cell Carcinomas. / Pathobiology / 78 / 171 / 180 / 2011 /

Hasebe D, Kobayashi T, Hasegawa M, Iwamoto T, Kato K, Izumi N, Takata Y, Saito C. / Changes in oropharyngeal airway and respiratory function during sleep after orthognathic surgery in patients with mandibular prognathism. / Int J Oral Maxillofac Surg. / 40 / :584 / 592 / 2011 /

Hasegawa M, Cheng J, Maruyama S, Yamazaki M, Saku T / Sialadenitis as a possible risk factor for salivary gland cancer. / International Journal of Oral and Maxillofacial Surgery, / 40 / 1449 / 1450 / 2011 /

Mikami T, Cheng J, Maruyama S, Kobayashi T, Funayama A, Yamazaki M, Adeola HA, Wu L, Shingaki S, Saito C, Saku T / Emergence of keratin 17 vs. loss of keratin 13: Their reciprocal immunohistochemical profiles in oral carcinoma in situ. / Oral Oncol / 47 / 497 / 503 / 2011 /

Niimi K, Yoshizawa M, Sugai T, Kobayashi T, Ono K, Takagi R, Okiji T, Saito C / Clinical Study on Root Resorption of Auto-transplanted Teeth with Complete Root Formation. / Asian J. Oral Maxillofac Surg. / 23 / 18 / 24 / 2011 /

Yamada K., Hoshina H., Arashiyama T., Arasawa M., Arai Y., Uoshima K., Tanaka M., Nomura S / Immediate implant loading following computer-guided surgery. / J. Prosthodont Res / 55 / 562 / 265 / 2011 /

Hasegawa M, Cheng J, Maruyama S, Yamazaki M, Iida A, Takagi R, Tanaka R, Hayashi Y, Saito C, Saku T / Complication of adenoid cystic carcinoma and sialolithiasis in the submandibular gland: report of a case and its etiological background. / Int.J. Oral Maxillofac. Surg. / 40 / 647 / 650 / 2011 /

Ahsan MS, Maruyama S, Cheng J, Al-Eryani K, Yamazaki M, Hasegawa M, Tsuneki M, Saku T / Acetic acid treatment for wrinkle-free oral mucosal epithelia in paraffin section preparation. / Microsc Res Tech / 74 / 264 / 268 / 2011 /

Ahsan MS,Yamazaki M, Maruyama S, Kobayashi T, Ida-Yonemochi H, Hasegawa M, Henry Ademola A, Cheng J, Saku T / Differential expression of perlecan receptors, α-dystroglycan and integrin β1, before and after invasion of oral squamous cell carcinoma. / J Oral Pathol Med / 40 / 552 / 559 / 2011 /

Suda N, Ogawa T, Kojima T, Saito C, Moriyama K / Non-syndromic oligodontia with a novel mutation of PAX9. / J Dent Res. / 90 / 382 / 386 / 2010 /

Narimatsu K, Li M, de Freitas PH, Sultana S, Ubaidus S, Kojima T, Zhucheng L, Ying G, Suzuki R, Yamamoto T, Oda K, Amizuka N / Ultrastructural observation on cells meeting the histological criteria for preosteoblasts--a study in the mouse tibial metaphysis. / J Electron Micro / 59 / 427 / 436 / 2010 /

Niimi K, Yoshizawa M, Sugai T, Kobayashi T, Ono K, Takagi R, Okiji T, Saito C / Clinical Study on Root Resorption of Auto-transplanted Teeth with Complete Root Formation. / Asian J. Oral Maxillofac Surg / 23 / 18 / 24 / 2010 /

Sugai T, Yoshizawa M, Kobayashi T, Ono K, Takagi R, Kitamura N, Okiji T, Saito C / Clinical Study on Prognostic Factors of Autotransplantation of Teeth with Complete Root Formation. / Int J Oral Maxillofac Surg / 39 / 1193 / 1203 / 2010 /

Yohei Watanabe, Tamaki Mohri, Masaki Takeyama, Masaki Yamada, Takashi Okiji, Chikara Saito, and Isao Saito / Long term observation of autotransplanted teeth with complete root formation in orthodontic patients. / American Journal of Orthodontics & Dentfacial Orthopedics / 138 / 720 / 726 / 2010 /

Sugai T, Yoshizawa M, Kobayashi T, Ono K, Takagi R, Kitamura N, Okiji T, Saito C / Clinical study on prognostic factors for autotransplantation of teeth with complete root formation / Int J Oral Maxillofac Surg / 39 / 1193 / 1203 / 2010 /

Tilakaratne WM, Kobayashi T, Ida-Yonemochi H,Swelam W, Yamazaki M, Mikami T, Alvarado CG,Shahidul AM, Maruyama S, Cheng J, Saku T / Matrix metalloproteinase 7 and perlecan in oralepithelial dysplasia and carcinoma in situ: an aidfor histopathologic recognition of their cellproliferation centers. / J Oral Pathol Med / 38 / 348 / 355 / 2009 /

Maruyama S, Cheng J, Shingaki S, Tamura T, Asakawa S, Minoshima S, Shimizu Y, Shimizu N, Saku T / Establishment and characterization of pleomorphic adenoma cell systems: an in-vitro demonstration of carcinomas arising secondarily from adenomas in the salivary gland. / BioMed Central Cancer, / 9 / 247 / 247 / 2009 /

Saito S, Suzuki A, Nozawa-Inoue K, Kawano Y, Hoshino M, Saito C, Maeda T. / Immunohistochemical detection of nestin in the periodontal Ruffini endings of the rat incisor. / Neurosci Lett. / 449 / 195 / 200 / 2009 /

Ishiguro K, Kobayashi T, Kitamura N, Saito C. / Relationship between severity of sleep-disordered breathing and craniofacial morphology in Japanese male patients. / Oral Surg Oral Med Oral Pathol Oral Radiol Endod. / 107 / 343 / 349 / 2009 /

Mir Nowazesh Ali, Ejiri S, Kobayashi T, DRezwana Binte Anwar, Oda K, Ohshima H, Saito C / Histological study of the cellular events during rat mandibular distraction osteogenesis / Oral Surg Oral Med Oral Pathol Oral Radiol Endod / 107 / 325 / 335 / 2009 /

Kitagawara K, Kobayashi T, Goto H, Yokobayashi T, Kitamura N, Saito C / Effects of mandibular setback surgery on oropharyngeal airway and arterial oxygen saturation / Int J Oral Maxillofac Surg / 37 / 328 / 333 / 2008 /

Izumi N, Yoshizawa M, Ono Y, Kobayashi T, Hamamoto Y, Saito C / Periodontal regeneration of transplanted rat teeth subcutaneously after cryopreservation / Int J Oral Maxillofac Surg / 36 / 838 / 844 / 2007 /

Kojima T, Amizuka N, Suzuki A, Freitas PHL, Yoshizawa M, Kudo A, Saito C, Maeda T / Histological examinations on the bone regeneration achieved by combining grafting with hydroxyapatite and thermoplastic bioresorbable plates / J Bone Miner Metab / 25 / 361 / 373 / 2007 /

Kojima T, Freitas PHL, Ubidus S, Suzuki A, Li M, Yoshizawa M, Oda M, Maeda T, Kudo A, Saito C, Amizuka N / Histochemical examinations on the regenerated cortical bone induced by thermoplastic bioresorbable plates / BioMed Res / 28 / 219 / 229 / 2007 /

Li M, Sasaki T, Ono K, Freitas PHL, Sobhan U, Kojima T, Shimomura J, Oda K, Amizuka N / Distribution of macrophages, osteoclasts and the B-lymphocyte lineage in osteolytic metastasis of mouse mammary carcinoma / BioMed. Res / 28 / 127 / 137 / 2007 /

Hirose S, Li M, Kojima T, Freitas PHL, Sobhan U, Oda K, Saito C, Amizuka N / A histological assessment on the distribution of the osteocytic lacunar canalicular system using silver staining / J. Bone Miner. Metab / 25 / 374 / 382 / 2007 /

Freitas PHL, Kojima T, Ubaidus S, Li M, Shang G, Takagi G, Maeda T, Oda K, Ozawa H, Amizuka N / Histological assessments on the abnormalities of epiphyseal chondrocytes with short term centrifugal loading / BioMed. Res / 28 / 191 / 203 / 2007 /

Nakanishi Y, Izumi K, Yoshizawa M, Saito C, Kawano Y, Maeda T / The expression and production of vascular endothelial growth factor in oral mucosa equivalents / Int J Oral Maxillofac Surg / 36 / 928 / 933 / 2007 /

Ohdaira F, Nakamura K, Nakayama H, Satoh M, Ohdaira T, Nakamata M, Kohno M, Iwashima A, Onda A, Kobayashi Y, Fujimori K, Kiguchi T, Izumi S, Kobayashi T, Shinoda H, Takahashi S, Gejyo F, Yamamoto M / Demographic characteristics of 3,659 Japanese patients with obstructive sleep apnea–hypopnea syndrome diagnosed by full polysomnography: associations with apnea-hypopnea index / Sleep and Breathing. / 11 / 93 / 101 / 2007 /

Nishizawa R, Nagata M, Noman A A, Kitamura N, Fujita H, Hoshina H, Kubota T, Itagaki M, Shingaki S, Ohnishi M, Kurita H, Katsura K, Saito C, Yoshie H, Takagi R / The 2G allele of promoter region of matrix metalloproteinase-1 as an essential pre-condition for the early onset of oral squamous cell carcinoma / BMC Cancer / 7 / 187 / 187 / 2007 /

Amizuka N,Uchida T,Inoue KN,Kawano Y,Suzuki A,Li M,Nasu M, Kojima T,Sakagami N,Ozawa H, Maeda T / Ultrastructural images of enamel tufts in human permanent teeth. / J Oral Biosci / 47 / 33 / 41 / 2005 /

Ida HY,Wael S,Saito C,Saku T / Angiolipoma of the buccal mucosa:a possible role of mast cell-derived VEGF in its enhanced vascularity. / J Oral Pathol Med / 34 / 59 / 61 / 2005 /

Song J,Izumi K,Lanigan T,Feinberg SE / Development and Characterization of a Canine Oral Mucosa Equivalent in A Serum-free Environment. / Biomedical Materials Research / 71A / 143 / 153 / 2004 /

Yoshizawa M,Feinberg SE,Marcelo CL,Elner VM / Ex Vivo-Produced Human Conjunctiva and Oral Mucosa Equivalents Grown in a Serum-free Culture System. / J Oral Maxillofac Surg / 62 / 980 / 988 / 2004 /

Fujita H,Nagata M,Hosina H,Nagashima K,Seki Y,Tanaka K,Nishizawa R, Shingaki S,Ohnishi M,Takagi R / Clinical significance and usefulness of quantification of telomerase activity in oral malignant and nonmalignant lesions. / Int J Oral maxillofac Surg / 33 / 693 / 699 / 2004 /

Rahima B,Shingaki S,Nagata M,Saito C / Prognostic significance of perineural invasion in oral and oropharyngeal carcinoma. / Oral Surg Oral Med Oral Pathol Oral Radiol Endod / 97 / 423 / 431 / 2004 /

Hamdy M,Jun C,Suzuki M,Takata Y,Saito C,Hayashi T,Saku T / Benign Lymphoepithelial lesion of minor salivary gland:report of a case involving the palatal mucosa. / Oral Oncology EXTRA / 40 / 113 / 116 / 2004 /

Izumi K, Terashi H, Marcelo CL, Feinberg SE / Evaluation of Transplanted Tissue-engineered Oral Mucosa Equivalents to SCID Mice. / Tissue Engineering / 9 / 163 / 174 / 2003 / Online Journal

Izumi K,Feinberg SE,Iida A,Yoshizawa M / Intraoral grafting of an ex vivo produced oral mucosa equipment. Apreliminary report. / Int J Oral Maxillofac Surg / 32 / 188 / 197 / 2003 / Online Journal

Gong L,Hoshi K,Ejiri S,Nakajima T,Shingaki S,Ozawa H / Bisphaphonate incadronate inhibits maturation of ectopic bone induced by recombinant human bone morphogenetic protein 2. / J Bone miner Metab / 21 / 5 / 11 / 2003 / Online Journal

Shingaki S, Takada M,Sasai K,Bibi R,Kobayashi T,Nomura T,Saito C / Impact of Lymph node metastasis on the pattern of failure and survival in oral carcinomas. / Am J Surg / 185 / 278 / 284 / 2003 / Online Journal

Nomura T, Gold E, Powers MP, Shingaki S, Katz JL / Micromechanics/Structure relationships in the human mandible / Dental Material / 19 / 167 / 173 / 2003 / Online Journal

Suzuki I., Yamada K., Yamakawa T., Hashiba M., Akazawa K. / Delivery of Medical Multimedia Contents through the TCP/IP Network Using RealSystem. / Computer Methods and Programs in Bilmedicine / 70 / 253 / 258 / 2003 / Online Journal

Oda Y., Cheng J., Nakajima T., Saku T. / Expression of Adhesion Molecules in the Vascular Invasion Process of O-1N, Hamster Squamous Cell Carcinoma with High Potential of Lymph Node Metastasis / Oral Med Pathol / 7 / 9 / 18 / 2002 /

Shingaki S, Nomura T, Takada M, Kobayashi T, Suzuki I, Nakajima T. / Squamous cell carcinoma of the mandibular alveolus: Analysis of prognostic factors. / Oncology / 62 / 17 / 24 / 2002 / Online Journal

Ono Y., Nakanishi Y., Gotoh M., Sakamoto M., Hirohashi S. / Epidermal Growth Factor Receptor Gene Amplification is Correlated with Laminin-5 gamma 2 Chain Expression in Oral Squamous Cell Carcinoma Cell Lines. / Cancer Lettes / 175 / 197 / 204 / 2002 / Online Journal

Hamamoto Y, Kawasaki N, Jarnbring F, Hammarstrom L / Effects and distribution of the enamel matrix derivative Emdogain in the periodontal tissue of rat molars transplanted to the abdominal wall. / Dental Traumatology / 18 / 12 / 23 / 2002 / Online Journal

Niimi K, Yoshizawa M, Nakajima T, Saku T. / Vascular invasion in squamous cell carcinoma of human oral mucosa / Oral Oncology / 37 / 357 / 364 / 2001 / Online Journal

Kobayashi, T., Honma, K., Shingaki, S., Nakajima, T. / Changes in masticatory function after orthognathic treatment in patients with mandibular prognathism. / Br J Oral Maxillofac Surg / 39 / 260 / 265 / 2001 / Online Journal

Izumi K, Iida A, Yoshizawa M, Suzuki I, Takagi R, Feinberg SE / Clinical Application of a Tissue Engineered Ex Vivo-Produced Oral Mucosal Equivalent: A Preliminary Report. / J Oral Maxillofac Surg / 59 / 23 / 24 / 2001 /

Shimizu N, Kuwano R, Shingaki S, Nakajima T. / Detection of hamster squamous cell carcinoma cells (O-1N) in blood and lymph nodes by reverse transcriptase-polymerase chain reaction for cytokeratin 19. / Oral Med Pathol / 5 / 71 / 76 / 2000 /

Kobayashi, T., Honma, K., Hamamoto, Y., Shingaki, S., Hanada, K., Nakajima, T. / Effects of wire and miniplate fixation on mandibular stability and TMJ symptoms following orthognathic surgery. / Clin Orthod Res / 3 / 155 / 161 / 2000 /

Izumi K, Terashi H, Marcelo CL, Feinberg SE / Development and Characterization of A Tissue Engineered Human Oral Mucosa Equivalent Produced In A Serum-free Culture System. / J Dent Res / 79 / 798 / 805 / 2000 / Online Journal

Shingaki S, Nomura T, Takada M, Kobayashi T, Suzuki I, Nakajima T. / The impact of extranodal spread of lymph node metastases in squamous cell carcinoma of the head and neck / Int J Oral Maxillofac Surg / 28 / 279 / 284 / 1999 / Online Journal

Ono Y, Nakanishi Y, Ino Y, Niki T, Yamada T, Yoshimura K, Saikawa M, Nakajima T, Hirohashi S. / Clinicopathologic significance of laminin-5 gannma 2 chain expression in squamous cell carcinoma of the tongue. / Cancer / 85 / 2315 / 2321 / 1999 / Online Journal

Kobayashi, T., Honma, K., Izumi, K., Hayashi, T., Shingaki, S., Nakajima, T. / Temporomandibular joint symptoms and disk displacement in patients with mandibular prognathism. / Br J Oral Maxillofac Surg / 37 / 455 / 458 / 1999 / Online Journal

Inoue, M., Yamamura, K., Nakajima, T., Yamada Y. / Changes inreflex response of the masseter and digastric muscle during sleep in freely begaving rabbits. / Neuroscience Res / 34 / 37 / 44 / 1999 / Online Journal

Izumi K, Takacs G, Terashi H, Feinberg SE / Ex Vivo Development of a Composite Human Oral Mucosal Equivalent. / J Oral Maxillofac Surg / 57 / 571 / 577 / 1999 / Online Journal

Honma, K., Kobayashi, T., Nakajima, T., Hayashi, T. / Computed tomographic evaluation of bone formation after secondary bone grafting of alveolar clefts. / J Oral Maxillofac Surg / 57 / 1209 / 1213 / 1999 / Online Journal

Mahmood JU, Nomura T, Suzuki K, Shingaki S, Nakajima T. / Heterogeneity of squamous cell carcinoma of the head and neck in relation to clinicopathological parameters. / Br J Oral Maxillofac Surg / 36 / 446 / 452 / 1998 / Online Journal

Hamamoto Y. Hamamoto N. Nakajima T. Ozawa H. / Morphological changes of epithelial rests of Malassez in rat molars induced by local administration of N-methylnitrosourea / Arch Oral Biol / 43 / 899 / 906 / 1998 / Online Journal

Hamamoto N. Hamamoto Y. Kobayashi T. / Tooth autotransplantation into the bone-grafted alveolar cleft: report of two cases with histologic findings. / J Oral Maxillofac Surg / 56 / 1451 / 1456 / 1998 /

Nomura, T., Suzuki, I., Kohno, M., Shingaki, S., Nakajima, T. / Reconstruction of the mandible with bone grafts and metal plates: Analysis of 42 cases. / Asian J.Oral Maxillofac Surg / 10 / 7 / 15 / 1998 /

Nomura, T., Shingaki, S., Nakajima, T. / Current evaluation of dental implants: a review of the literature. / J Long-Term Effects Med Implants / 8 / 175 / 192 / 1998 / Online Journal

Nomura, T., Suzuki, I., Kohno, M., Shingaki, S., Nakajima, T. / Clinical Evaluation of Vascularized Fibula Grafts for Mandibular Reconstruction in 6 Cases. / Asian J.Oral Maxillofac Surg / 9 / 31 / 39 / 1997 /

Hamamoto Y, Takahashi K, Sakurai H, Akiba K, Izumi N, Kanoh H, Yoshizawa M, Saito C. / The use of enamel matrix derivative (Emdogain®) for improvement of probing attachment level of the autotransplanted teeth. / Dental Traumatology / 21 / 336 / 340 / 2005 / Online Journal






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